|Pronunciation||sar"e sye' kleen|
|Side effects||Nausea, sunburns, dizziness, Clostridium difficile infection|
|Typical dose||60 to 150 mg OD|
|Chemical and physical data|
|Molar mass||487.509 g·mol−1|
|3D model (JSmol)|
Common side effects include nausea. Other side effects may include sunburns, dizziness, Clostridium difficile infections. Use during pregnancy may harm the baby. It is in the tetracycline class.
Sarecycline was approved for medical use in the United States in 2018. In the United States it costs about 750 USD per month as of 2021. It is not available in Europe or the United Kingdom as of 2021.
The spectrum of activity is limited to clinically relevant Gram-positive bacteria, mainly Cutibacterium acnes, with little or no activity against Gram-negative bacterial microflora commonly found in the human gastrointestinal tract. Sarecycline has not been tested in spirochetes.
It is taken at a dose of 60 to 150 mg once per day depending on a person's weight.
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