SYT13

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SYT13
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSYT13, synaptotagmin 13
External IDsOMIM: 607716 MGI: 1933945 HomoloGene: 10823 GeneCards: SYT13
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020826
NM_001247987

NM_030725

RefSeq (protein)

NP_001234916
NP_065877

NP_109650

Location (UCSC)Chr 11: 45.24 – 45.29 MbChr 2: 92.75 – 92.79 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Synaptotagmin-13 is a protein that in humans is encoded by the SYT13 gene.[5][6]

Function

SYT13 belongs to the large synaptotagmin protein family. All synaptotagmins show type I membrane topology, with an extracellular N terminus, a single transmembrane region, and a cytoplasmic C terminus containing tandem C2 domains. Major functions of synaptotagmins include vesicular traffic, exocytosis, and secretion.[supplied by OMIM][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000019505 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000027220 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Fukuda M, Mikoshiba K (March 2001). "Characterization of KIAA1427 protein as an atypical synaptotagmin (Syt XIII)". The Biochemical Journal. 354 (Pt 2): 249–57. doi:10.1042/0264-6021:3540249. PMC 1221650. PMID 11171101.
  6. ^ a b "Entrez Gene: SYT13 synaptotagmin XIII".

Further reading

External links

  • Overview of all the structural information available in the PDB for UniProt: Q7L8C5 (Human Synaptotagmin-13 (SYT13)) at the PDBe-KB.