Rose spots are red macules 2-4 millimeters in diameter occurring in patients with enteric fever (which includes typhoid and paratyphoid). These fevers occur following infection by Salmonella typhi and Salmonella paratyphi respectively. Rose spots may also occur following invasive non-typhoid salmonellosis.
Rose spots are bacterial emboli to the skin and occur in approximately 1/3 of cases of typhoid fever. They are one of the classic signs of untreated disease, but can also be seen in other illnesses as well including shigellosis and nontyphoidal salmonellosis. They appear as a rash between the seventh and twelfth day from the onset of symptoms. They occur in groups of five to ten lesions on the lower chest and upper abdomen, and they are more numerous following paratyphoid infection. Rose spots typically last three to four days.
- Gale's Encyclopedia of Medicine, published by Thomas Gale in 1999, ISBN 978-0-7876-1868-1
- "www.healthatoz.com". Typhoid fever article which includes information on rose spots. Archived from the original on 21 February 2006. Retrieved 17 February 2006.
- "Organizational home". Centers for Disease Control. Retrieved 17 February 2006.