Rifamycin

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Rifamycin
Rifamycin SV.svg
Rifamycin SV stick 6BEB.png
Names
Trade namesAemcolo
Other namesRifamycin sodium
Clinical data
Drug classRifamycins[1]
Main usesTravelers' diarrhea[1]
Side effectsHeadache, constipation[1]
Pregnancy
category
  • US: N (Not classified yet)
Routes of
use
By mouth
External links
AHFS/Drugs.comMonograph
US NLMRifamycin
MedlinePlusa619010
Legal
License data
Legal status
Chemical and physical data
FormulaC37H47NO12
Molar mass697.778 g·mol−1
3D model (JSmol)
  • CC1C=CC=C(C(=O)NC2=CC(=C3C(=C2O)C(=C(C4=C3C(=O)C(O4)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)C
  • InChI=1S/C37H47NO12/c1-16-11-10-12-17(2)36(46)38-23-15-24(40)26-27(32(23)44)31(43)21(6)34-28(26)35(45)37(8,50-34)48-14-13-25(47-9)18(3)33(49-22(7)39)20(5)30(42)19(4)29(16)41/h10-16,18-20,25,29-30,33,40-44H,1-9H3,(H,38,46)/b11-10+,14-13+,17-12-/t16-,18+,19+,20+,25-,29-,30+,33+,37-/m0/s1
  • Key:HJYYPODYNSCCOU-ODRIEIDWSA-N

Rifamycin, sold under the brand name Aemcolo, is an antibiotics used to treat travelers' diarrhea.[1] It is not recommended if a fever or bloody stool is present.[1] It is taken by mouth.[1]

Common side effects include headache and constipation.[1] Other side effects may include Clostridium difficile associated diarrhea.[2] Safety in pregnancy and breastfeeding is unclear.[3] It is in the rifamycins class of medications.[1]

Rifamycin was approved for medical use in the United States for treatment is 2018.[1] In the United States a course of treatment costs about 190 USD as of 2021.[4]

Medical uses

Dosage

It is taken at a dose of 388 mg twice per day for three days.[1]

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 "Rifamycin Monograph for Professionals". Drugs.com. Archived from the original on 25 January 2021. Retrieved 17 October 2021.
  2. "DailyMed - AEMCOLO- rifamycin tablet, delayed release". dailymed.nlm.nih.gov. Archived from the original on 17 October 2021. Retrieved 17 October 2021.
  3. "Rifamycin (Aemcolo) Use During Pregnancy". Drugs.com. Archived from the original on 17 April 2021. Retrieved 17 October 2021.
  4. "Aemcolo Prices and Aemcolo Coupons - GoodRx". GoodRx. Retrieved 17 October 2021.

External links

External sites:
Identifiers: