60S ribosomal protein L29

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RPL29
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesRPL29, HIP, HUML29, RPL29P10, RPL29_3_370, ribosomal protein L29
External IDsOMIM: 601832 HomoloGene: 133570 GeneCards: RPL29
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000992

n/a

RefSeq (protein)

NP_000983

n/a

Location (UCSC)Chr 3: 51.99 – 52 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

60S ribosomal protein L29 is a protein that in humans is encoded by the RPL29 gene.[3][4]

Function

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L29E family of ribosomal proteins. The protein is also a peripheral membrane protein expressed on the cell surface that directly binds heparin. Although this gene was previously reported to map to 3q29-qter, it is believed that it is located at 3p21.3-p21.2. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[4]

Interactions

RPL29 has been shown to interact with BLMH.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000162244 - Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Law PT, Tsui SK, Lam WY, Luk SC, Hwang DM, Liew CC, Lee CY, Fung KP, Waye MM (Apr 1996). "A novel cDNA encoding a human homologue of ribosomal protein L29". Biochim Biophys Acta. 1305 (3): 105–8. doi:10.1016/0167-4781(95)00224-3. PMID 8597591.
  4. ^ a b "Entrez Gene: RPL29 ribosomal protein L29".
  5. ^ Koldamova RP, Lefterov IM, DiSabella MT, Almonte C, Watkins SC, Lazo JS (Jun 1999). "Human bleomycin hydrolase binds ribosomal proteins". Biochemistry. 38 (22): 7111–7. doi:10.1021/bi990135l. PMID 10353821.

Further reading

External links

  • Overview of all the structural information available in the PDB for UniProt: P47914 (60S ribosomal protein L29) at the PDBe-KB.