Prosidol
Jump to navigation
Jump to search
Clinical data | |
---|---|
ATC code |
|
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
Chemical and physical data | |
Formula | C18H27NO3 |
Molar mass | 305.418 g·mol−1 |
3D model (JSmol) | |
| |
| |
(verify) |
Prosidol is an opioid analgesic that is an analogue of prodine. It was originally discovered by J.F. MacFarlan and Co. in the 1950s.[1] It was further developed in Russia in the 1990s during research into the related drug pethidine.[2]
Prosidol has seen some clinical use, but is still a relatively new drug and does not yet have an extensive history of use. It produces similar effects to other opioids, such as analgesia and sedation, along with side effects such as nausea, itching, vomiting and respiratory depression which may be harmful or fatal.[3][4]
References
- ^ US 2960507, "Piperidine compounds"
- ^ Osipova NA, Novikov GA, Vetsheva MS, Prokhorov BM, Beresnev VA, Loseva NA, Zemskaia SI, Smolina TA (1994). "[First experience in the use of a new Russian narcotic analgesic prosidol in oncology]". Anesteziologiia I Reanimatologiia (in Russian) (4): 53–7. PMID 7802322.
- ^ Osipova NA (1996). "[The problem of opioid tolerance and dependence during clinical use thereof]". Anesteziologiia I Reanimatologiia (in Russian) (4): 17–21. PMID 8975562.
- ^ Abuzarova GR (2001). "[Prosidol, an original Russian opioid, in the treatment of pain syndromes]". Anesteziologiia I Reanimatologiia (in Russian) (5): 74–7. PMID 11757313.
Categories:
- CS1 Russian-language sources (ru)
- Articles with short description
- Short description matches Wikidata
- Drugs not assigned an ATC code
- Articles without EBI source
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Articles without UNII source
- Drugs with no legal status
- 4-Phenylpiperidines
- Synthetic opioids
- Propionate esters
- Ethers
- Mu-opioid receptor agonists
- All stub articles
- Analgesic stubs