|Pronunciation||oz en ox' a sin|
|Trade names||Ozanex; Xepi|
|Drug class||Antibiotic (quinolone)|
|Chemical and physical data|
|Molar mass||363.417 g·mol−1|
|3D model (JSmol)|
Ozenoxacin, sold under the brand names Ozanex and Xepi, is an antibiotic used to treat impetigo. This includes impetigo due to methicillin-resistant S. aureus (MRSA). It is applied to the skin as a cream.
As little is absorbed through the skin; side effects are uncommon. Side effects may include seborrheic dermatitis. It is not expected to be harmful in pregnancy or breastfeeding. It is a quinolone and works by blocking DNA gyrase A and topoisomerase IV.
Ozenoxacin was approved for medical use in the United States and Canada in 2017. In the United States a 30 gram tube of 1% cream costs about 340 USD as of 2021. This amount in Canada costs about 53 CAD.
It is used as a 1% cream applied twice daily for 5 days in those over the age of 2 months.
- "DailyMed - XEPI- ozenoxacin cream". dailymed.nlm.nih.gov. Retrieved 10 November 2021.
- Robertson, Dirk B.; Maibach, Howard I. (2020). "61. Dermatologic pharmacology". In Katzung, Bertram G.; Trevor, Anthony J. (eds.). Basic and Clinical Pharmacology (15th ed.). New York: McGraw-Hill. p. 1112. ISBN 978-1-260-45231-0.
- "Xepi- ozenoxacin cream". DailyMed. 30 January 2020. Retrieved 13 October 2020.
- "Ozenoxacin Monograph for Professionals". Drugs.com. Retrieved 10 November 2021.
- Canada, Health (30 June 2017). "Notice: Prescription Drug List (PDL): Multiple Additions [2017-06-23]". www.canada.ca. Retrieved 10 November 2021.
- "Xepi Prices, Coupons & Patient Assistance Programs". Drugs.com. Retrieved 10 November 2021.
- "Pharmacoeconomic Review Report" (PDF). CADTH. Retrieved 10 November 2021.