Oxotremorine
Jump to navigation
Jump to search
Clinical data | |
---|---|
Pregnancy category |
|
Routes of administration | Oral, intravenous |
ATC code |
|
Legal status | |
Legal status |
|
Identifiers | |
| |
CAS Number | |
IUPHAR/BPS | |
ChemSpider | |
UNII | |
ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.000.662 |
Chemical and physical data | |
Formula | C12H18N2O |
Molar mass | 206.289 g·mol−1 |
3D model (JSmol) | |
| |
| |
(what is this?) (verify) |
Oxotremorine is a drug that acts as a selective muscarinic acetylcholine receptor agonist.[1]
Oxotremorine produces ataxia, tremor and spasticity, similar to those symptoms seen in Parkinsonism, and has thus become a research tool in experimental studies aimed at determining more effective anti-Parkinsonian drugs.[2]
Oxotremorine also produces antipsychotic effects.[3]
References
- ^ Tang C, Castoldi AF, Costa LG (April 1993). "Effects of the muscarinic agonist oxotremorine on membrane fluidity in rat lymphocytes". Biochemistry and Molecular Biology International. 29 (6): 1047–54. PMID 8330013. INIST 4025194.
- ^ Craig CR, Stitzel RE, eds. (2004). Modern Pharmacology with Clinical Applications. Lippincott Williams & Wilkins. ISBN 978-0-7817-3762-3.[page needed]
- ^ Maehara S, Hikichi H, Satow A, Okuda S, Ohta H (November 2008). "Antipsychotic property of a muscarinic receptor agonist in animal models for schizophrenia". Pharmacology, Biochemistry, and Behavior. 91 (1): 140–9. doi:10.1016/j.pbb.2008.06.023. PMID 18651995. S2CID 12225821. INIST 20678587.
See also
Categories:
- Wikipedia articles needing page number citations from January 2021
- Articles with short description
- Short description matches Wikidata
- Drugs not assigned an ATC code
- Drugs with non-standard legal status
- Articles with changed ChemSpider identifier
- Articles with changed EBI identifier
- ECHA InfoCard ID from Wikidata
- Articles with changed InChI identifier
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Drugs with no legal status
- Drugboxes which contain changes to verified fields
- Drugboxes which contain changes to watched fields
- Alkyne derivatives
- Pyrrolidones
- Experimental drugs
- All stub articles
- Nervous system drug stubs