Nocardia farcinica

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Nocardia farcinica
Scientific classification edit
Domain: Bacteria
Phylum: Actinomycetota
Class: Actinomycetia
Order: Mycobacteriales
Family: Nocardiaceae
Genus: Nocardia
N. farcinica
Binomial name
Nocardia farcinica
Trevisan 1889 (Approved Lists 1980)
Type strain
ATCC 3318
CCUG 10109
CCUG 27778
CCUG 48656
CIP 104775
DSM 43257
DSM 43578
DSM 43665
IEGM 621
IFO 15532
JCM 3088
M. Goodfellow N898/ATCC 3318
NBRC 15532
NCTC 11134
NRRL B-2089
  • "Nocardia blackwellii" (Erikson 1935) Waksman and Henrici 1948

Nocardia farcinica is a species of bacteria, once thought to be associated with farcy, and a member of the genus Nocardia. This species is very similar in phenotype to Nocardia asteroides, to the degree that some isolates of N. asteroides were later found to be Nocardia farcinica.[3]


N. farcinica contains a 6 million base pair genome with an average GC content of 70.8%. A sequenced strain, IFM 10152, is also known to contain two plasmids, pNF1 pNF2. The chromosome encodes 5,674 potential protein-coding open reading frames. This genome may have undergone numerous gene duplication events as a result of adapting to new environments.[4]


a)Nocardia farcinica showing Gram-positive rod-shaped bacteria b) stain showing partial acid-fast reaction

N. farcinica may be a causative agent of nocardiosis[5] or of secondary infections in immunocompromised patients.[6]

Strains of this species have been isolated from human brain abscesses.[7]


  1. Kämpfer P, Dott W, Kroppendstedt RM. (1990). "Numerical classification and identification of some nocardioform bacteria". The Journal of General and Applied Microbiology. 36 (5): 309–331. doi:10.2323/jgam.36.309.
  2. Parte, A.C. "Nocardia". LPSN. Archived from the original on 2023-08-11. Retrieved 2023-01-29.
  3. Wallace RJ Jr.; Tsukamura, M; Brown, BA; Brown, J; Steingrube, VA; Zhang, YS; Nash, DR (December 1990). "Cefotaxime-resistant Nocardia asteroides strains are isolates of the controversial species Nocardia farcinica". Journal of Clinical Microbiology. 28 (12): 2726–32. doi:10.1128/JCM.28.12.2726-2732.1990. PMC 268263. PMID 2280003.
  4. Ishikawa, J; Yamashita, A; Mikami, Y; Hoshino, Y; Kurita, H; Hotta, K; Shiba, T; Hattori, M (Oct 12, 2004). "The complete genomic sequence of Nocardia farcinica IFM 10152". Proceedings of the National Academy of Sciences of the United States of America. 101 (41): 14925–30. doi:10.1073/pnas.0406410101. PMC 522048. PMID 15466710.
  5. Holm, P (July 1975). "Seven cases of human nocardiosis caused by Nocardia farcinica". Sabouraudia. 13 (2): 161–9. doi:10.1080/00362177585190301. PMID 1162538.
  6. Torres, O. H.; Domingo, P.; Pericas, R.; Boiron, P.; Montiel, J. A.; Vázquez, G. (3 April 2000). "Infection Caused by Nocardia farcinica : Case Report and Review". European Journal of Clinical Microbiology & Infectious Diseases. 19 (3): 205–212. doi:10.1007/s100960050460. PMID 10795594. S2CID 6487051.
  7. Malincarne, Lisa; Marroni, Massimo; Farina, Claudio; Camanni, Guido; Valente, Marina; Belfiori, Barbara; Fiorucci, Stefano; Floridi, Piero; Cardaccia, Angela; Stagni, Giuliano (1 May 2002). "Primary brain abscess with Nocardia farcinica in an immunocompetent patient". Clinical Neurology and Neurosurgery. 104 (2): 132–135. doi:10.1016/S0303-8467(01)00201-3. PMID 11932043. S2CID 35619104.

Further reading

  • Malla, Sailesh; Pandey, Ramesh Prasad; Kim, Byung-Gee; Sohng, Jae Kyung (22 April 2013). "Regiospecific modifications of naringenin for astragalin production in Escherichia coli". Biotechnology and Bioengineering. 110 (9): 2525–2535. doi:10.1002/bit.24919. PMID 23568509. S2CID 205503095.
  • Toyomitsu, Sawai (April 8, 2014). "A case of community-acquired pneumonia due to influenza A virus and Nocardia farcinica co-infection". Journal of Infection and Chemotherapy. 20 (8): 506–508. doi:10.1016/j.jiac.2014.04.008. PMID 24855916.

External links