Naproxen/esomeprazole

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Naproxen/esomeprazole
Combination of
NaproxenNSAID
Esomeprazole magnesiumProton pump inhibitor
Names
Trade namesVimovo
Clinical data
Pregnancy
category
  • AU: C[1]
  • US: C (Risk not ruled out)[1]
Routes of
use		By mouth
External links
AHFS/Drugs.comProfessional Drug Facts
Legal
Legal status

Naproxen/esomeprazole, sold under the brand name Vimovo, is a pain medication that is taken by mouth, with delayed release of esomeprazole, a proton pump inhibitor (PPI)"[2] and naproxen. It is approved in the United States for osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.[3] The inclusion of a PPI is intended to decrease the risk of gastric ulcers from treatment with nonsteroidal anti-inflammatory drugs.[3]

It is available as a generic medication.[4] It was originally produced by AstraZeneca. In the United States it costs about 740 USD per month as of 2020.[5] The cost of the individual components; however, is about 23 USD for esomeprazole and 10 USD for naproxen.[6][7]

Side effects

See also: Naproxen § Adverse effects, and Esomeprazole § Adverse effects

Society and culture

Vimovo was acquired by the Ireland-based company, Horizon Pharma on November 19, 2013. AstraZeneca retained "ex-U.S. rights to VIMOVO".[2]

Cost

The medication cost in the U.S. for 60 tablets in delayed release tablet 20 mg-375 mg is $1,082 (USD)[8]

  • EsomeprazoleMagnesiumNaproxen prescriptions (US)

  • EsomeprazoleMagnesiumNaproxen costs (US)

The cost of the naproxen and esomeprazole separately in 2017 was $40 a month. Horizon Pharma bills insurance companies $3,252 a month for Vimovo.[9] According to The Atlantic, "since 2014, Horizon Pharma’s net sales have been more than $455 million".[9]

References

  1. ↑ 1.0 1.1 "Esomeprazole / naproxen (Vimovo) Use During Pregnancy". Drugs.com. 11 September 2019. Retrieved 17 August 2020.
  2. ↑ 2.0 2.1 "Horizon Pharma Announces Agreement to Acquire U.S. Rights to VIMOVO(R) and Provides 2014 Guidance". Horizon Pharma, Inc. Deerfield, Illinois. November 19, 2013.(NASDAQ: HZNP)
  3. ↑ 3.0 3.1 "VIMOVO® (naproxen and esomeprazole magnesium) Tablets". Horizon Pharma. nd. Retrieved June 20, 2017.
  4. ↑ https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=022511
  5. ↑ "Vimovo Prices, Coupons & Savings Tips". GoodRx. Retrieved 15 November 2020.
  6. ↑ "Esomeprazole Prices, Coupons & Savings Tips". GoodRx. Retrieved 15 November 2020.
  7. ↑ "Naproxen Prices, Coupons & Savings Tips". GoodRx. Retrieved 15 November 2020.
  8. ↑ "Esomeprazole/naproxen Prices, Coupons & Patient Assistance Programs". Drugs.com. Retrieved 29 March 2021.
  9. ↑ 9.0 9.1 Allen, Marshall (June 20, 2017). "How Two Common Medications Became One $455 Million Specialty Pill". The Atlantic. Retrieved June 20, 2017. After I was prescribed a brand-name drug I didn’t need and given a coupon to cover the out-of-pocket costs, I discovered yet another reason why Americans pay too much for health care.

External links

Identifiers:
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