NRD1

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NRDC
Identifiers
AliasesNRDC, hNRD1, hNRD2, NRD1, nardilysin convertase, nardilysin
External IDsOMIM: 602651 MGI: 1201386 HomoloGene: 68260 GeneCards: NRDC
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001101662
NM_001242361
NM_002525

NM_146150
NM_001346554
NM_001347169

RefSeq (protein)

NP_001095132
NP_001229290
NP_002516

NP_001333483
NP_001334098
NP_666262

Location (UCSC)Chr 1: 51.79 – 51.88 MbChr 4: 108.86 – 108.92 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Nardilysin is a protein that in humans is encoded by the NRD1 gene.[5][6][7]


Interactions

NRD1 has been shown to interact with Heparin-binding EGF-like growth factor.[8]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000078618 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000053510 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Hospital V, Prat A, Joulie C, Cherif D, Day R, Cohen P (May 1998). "Human and rat testis express two mRNA species encoding variants of NRD convertase, a metalloendopeptidase of the insulinase family". Biochem J. 327 (3): 773–9. doi:10.1042/bj3270773. PMC 1218856. PMID 9581555.
  6. ^ Fumagalli P, Accarino M, Egeo A, Scartezzini P, Rappazzo G, Pizzuti A, Avvantaggiato V, Simeone A, Arrigo G, Zuffardi O, Ottolenghi S, Taramelli R (Apr 1998). "Human NRD convertase: a highly conserved metalloendopeptidase expressed at specific sites during development and in adult tissues". Genomics. 47 (2): 238–45. doi:10.1006/geno.1997.5078. PMID 9479496.
  7. ^ "Entrez Gene: NRD1 nardilysin (N-arginine dibasic convertase)".
  8. ^ Nishi, E; Prat A; Hospital V; Elenius K; Klagsbrun M (Jul 2001). "N-arginine dibasic convertase is a specific receptor for heparin-binding EGF-like growth factor that mediates cell migration". EMBO J. 20 (13). England: 3342–50. doi:10.1093/emboj/20.13.3342. ISSN 0261-4189. PMC 125525. PMID 11432822.

Further reading