|Other names||N-(3-Methyl-5-sulfamoyl-3H-1,3,4-thiadiazol-2-ylidene) ethanamide|
|Drug class||Carbonic anhydrase inhibitor|
|Side effects||Numbness, hearing problems, tiredness, nausea, diarrhea, sleepiness|
|Onset of action||Within 4 hrs|
|Duration of action||Up to 18 hrs|
|Elimination half-life||~14 hours|
|Chemical and physical data|
|Molar mass||236.26 g·mol−1|
|3D model (JSmol)|
|(what is this?)|
Methazolamide, sold under the brand name Neptazane among, is a medication used to treat increased intraocular pressure (IOP) including in glaucoma. It is taken by mouth. Effects begin within 4 hours and last for up to 18 hours.
Common side effects include numbness, hearing problems, tiredness, nausea, diarrhea, and sleepiness. Other side effects may include Stevens-Johnson syndrome. It is an carbonic anhydrase inhibitor which decreases the production of aqueous humor.
The typical dose is 50 to 100 mg two or three times per day.
- "Methazolamide Monograph for Professionals". Drugs.com. Retrieved 17 November 2021.
- Supuran, Claudiu T.; Nocentini, Alessio (17 July 2019). Carbonic Anhydrases: Biochemistry and Pharmacology of an Evergreen Pharmaceutical Target. Academic Press. p. 271. ISBN 978-0-12-816745-8.
- "Methazolamide Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 17 November 2021.