Measles hemagglutinin

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Hemagglutinin
Identifiers
OrganismMeasles virus (strain Edmonston)
SymbolH
PDB2RKC
UniProtP08362
Search for
StructuresSwiss-model
DomainsInterPro

Measles hemagglutinin is a hemagglutinin produced by measles virus.[1][2][3]

It attaches to CD46 using a dead neuraminidase domain.[4][5]

References

  1. ^ Pan CH, Jimenez GS, Nair N, et al. (August 2008). "Use of Vaxfectin adjuvant with DNA vaccine encoding the measles virus hemagglutinin and fusion proteins protects juvenile and infant rhesus macaques against measles virus". Clin. Vaccine Immunol. 15 (8): 1214–21. doi:10.1128/CVI.00120-08. PMC 2519314. PMID 18524884.
  2. ^ Tahara M, Takeda M, Shirogane Y, Hashiguchi T, Ohno S, Yanagi Y (May 2008). "Measles virus infects both polarized epithelial and immune cells by using distinctive receptor-binding sites on its hemagglutinin". J. Virol. 82 (9): 4630–7. doi:10.1128/JVI.02691-07. PMC 2293038. PMID 18287234.
  3. ^ Hashiguchi T, Kajikawa M, Maita N, et al. (December 2007). "Crystal structure of measles virus hemagglutinin provides insight into effective vaccines". Proc. Natl. Acad. Sci. U.S.A. 104 (49): 19535–40. Bibcode:2007PNAS..10419535H. doi:10.1073/pnas.0707830104. PMC 2148324. PMID 18003910.
  4. ^ Colf, LA; Juo, ZS; Garcia, KC (December 2007). "Structure of the measles virus hemagglutinin". Nature Structural & Molecular Biology. 14 (12): 1227–8. doi:10.1038/nsmb1342. PMID 18026116. S2CID 40292.
  5. ^ Nussbaum O, Broder CC, Moss B, Stern LB, Rozenblatt S, Berger EA (June 1995). "Functional and structural interactions between measles virus hemagglutinin and CD46". J. Virol. 69 (6): 3341–9. doi:10.1128/JVI.69.6.3341-3349.1995. PMC 189046. PMID 7745681.