Lutropin alfa

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Lutropin alfa
Names
Trade namesLuveris
Clinical data
Drug classLuteinising hormone (LH)[1]
Main usesInfertility in women due to hypopituitarism[1]
Side effectsHeadache, nausea, breast pain, abdominal pain, ovarian cysts[2]
Typical dose75 iu[3]
External links
AHFS/Drugs.comMonograph
US NLMLutropin alfa

Lutropin alfa, sold under the brand name Luveris, is a medication used to treat infertility in women due to hypopituitarism.[1] It is used together with follitropin alfa in those in who clomifene is not effective.[1][2] It is given by injection under the skin.[1]

Common side effects include headache, nausea, breast pain, abdominal pain, and ovarian cysts.[2] Other side effects may include blood clots, ovarian hyperstimulation syndrome, and multiple pregnancy.[1][2] It is a form of luteinising hormone (LH) made by recombinant DNA techniques.[1]

Lutropin alfa was approved for medical use in Europe in 2000.[3] In the United Kingdom it costs about £31 per 75 unit dose as of 2021.[1] It is not commercially available in the United States.[2]

Medical use

Dosage

It may be used at a dose of 75 units per day for infertility and it may be used up to 14 days.[2]

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 787. ISBN 978-0857114105.
  2. 2.0 2.1 2.2 2.3 2.4 2.5 "Lutropin Alfa Monograph for Professionals". Drugs.com. Retrieved 24 November 2021.
  3. 3.0 3.1 "Luveris". Retrieved 24 November 2021.