List of skin tumors associated with systemic syndromes

Many cutaneous neoplasms occur in the setting of systemic syndromes.

Cutaneous neoplasms associated with systemic syndromes
Neoplasm		Associated syndrome(s)
Trichoepithelioma		Brooke–Spiegler syndrome Rombo syndrome Rasmussen syndrome Brooke–Fordyce syndrome Bazex–Dupré–Christol syndrome
Cylindroma		Brooke–Spiegler syndrome Rasmussen syndrome
Psammomatous melanotic schwannoma		Carney complex
Sclerotic fibroma		Cowden syndrome
Trichilemmoma		Cowden syndrome Bannayan–Riley–Ruvalcaba syndrome
Sebaceous adenoma		Muir–Torre syndrome
Sebaceous carcinoma		Muir–Torre syndrome
Syringofibroadenoma		Clouston syndrome Schöpf–Schulz–Passarge syndrome
Syringoma		Down syndrome Nicolau–Balus syndrome Brooke–Spiegler syndrome^[1]
Trichodiscoma		Birt–Hogg–Dubé syndrome
Hidrocystoma		Schöpf–Schulz–Passarge syndrome
Pilomatricoma		Turner syndrome^[2]
Poroma		Schöpf–Schulz–Passarge syndrome Clouston syndrome
Spiradenoma		Brooke–Spiegler syndrome
Fibrofolliculoma		Birt–Hogg–Dubé syndrome
Clear cell acanthoma		Ichthyosis
Acrochordon		Birt–Hogg–Dubé syndrome
Epidermal inclusion cyst with pilomatrical differentiation		Gardner's syndrome
Gardner fibroma		Familial adenomatous polyposis and its variant, Gardner's syndrome^[3]
Dermoid tumor		Familial adenomatous polyposis and its variant, Gardner's syndrome^[3]

References

↑ Uede K, Yamamoto Y, Furukawa F. Brooke-Spiegler syndrome associated with cylindroma, trichoepithelioma, spiradenoma, and syringoma. J Dermatol. Jan 2004;31(1):32-8.
↑ Prevalence of Pilomatricoma in Turner Syndrome: Findings From a Multicenter Study. Handler MZ, Derrick KM, Lutz RE, Morrell DS, Davenport ML, Armstrong AW. JAMA Dermatol. 2013 Feb 20:1-6. doi:10.1001/2013.jamadermatol.115. PMID 23426075
↑ ^3.0 ^3.1 Baranov E, Hornick JL (March 2020). "Soft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the Head and Neck". Head and Neck Pathology. 14 (1): 43–58. doi:10.1007/s12105-019-01104-3. PMC 7021862. PMID 31950474.