List of chemotherapeutic agents

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Mechanisms of action of the main chemotherapeutic agents[1]

This is a list of chemotherapeutic agents, also known as cytotoxic agents or cytostatic drugs, that are known to be of use in chemotherapy for cancer. This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision. Each drug is listed once (at present), though it might fall in more than one subsection. A full alphabetical listing is included after the categorical listing.

The agents in this list are often combined into chemotherapy agent for polychemotherapy (combination chemotherapy). For example, the CHOP regimen consists of cyclophosphamide, doxorubicin, vincristine and prednisone.

Besides chemotherapy, medical oncology (pharmacotherapy for cancer) includes several noncytotoxic classes of therapy, such as hormonal therapy and targeted therapy (biologic therapy). Those agents are described in the relevant articles.

List

The list below is of chemotherapeutic agents:[2][3][4]

Alkylating agents

Main article: Alkylating agent

Anthracyclines

Main article: Anthracycline

Cytoskeletal disruptors

Main article: Taxane

Epothilones

Main article: Epothilone

Histone deacetylase inhibitors

Inhibitors of topoisomerase I

Main article: Topoisomerase inhibitor

Inhibitors of topoisomerase II

Main article: Topoisomerase II inhibitor

Kinase inhibitors

Main article: Kinase inhibitor

Nucleotide analogs and precursor analogs

Peptide antibiotics

Main article: Antimicrobial peptides

Platinum-based agents

Main article: Platinum-based antineoplastic

Retinoids

Vinca alkaloids and derivatives

Main article: Vinca alkaloid

Full alphabetical listing

The following list is alphabetical:[citation needed]

References

  1. ↑ Larionova, Irina; Cherdyntseva, Nadezhda; Liu, Tengfei; Patysheva, Marina; Rakina, Militsa; Kzhyshkowska, Julia (3 July 2019). "Interaction of tumor-associated macrophages and cancer chemotherapy". OncoImmunology. 8 (7): e1596004. doi:10.1080/2162402X.2019.1596004.
  2. ↑ "Cancer Drugs - NCI". www.cancer.gov. 30 January 2012. Archived from the original on 17 July 2024. Retrieved 5 August 2024.
  3. ↑ Amjad, Muhammad T.; Chidharla, Anusha; Kasi, Anup (2024). "Cancer Chemotherapy". StatPearls. StatPearls Publishing. Archived from the original on 2024-06-05. Retrieved 2024-08-05.
  4. ↑ Dembic, Zlatko (7 December 2020). "Antitumor Drugs and Their Targets". Molecules. 25 (23): 5776. doi:10.3390/molecules25235776. ISSN 1420-3049. Archived from the original on 7 October 2023. Retrieved 5 August 2024.
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