Linear and whorled nevoid hypermelanosis

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Linear and whorled nevoid hypermelanosis
Other names: Linear nevoid hyperpigmentation
Progressive cribriform zosteriform pigmented lesion with characteristic whorls and streaks on the right side of abdomen

Linear and whorled nevoid hypermelanosis (also known as "Linear nevoid hyperpigmentation," "Progressive cribriform and zosteriform hyperpigmentation," "Reticulate and zosteriform hyperpigmentation," "Reticulate hyperpigmentation of Iijima and Naito and Uyeno," "Zebra-like hyperpigmentation in whorls and streaks," and "Zebra-line hyperpigmentation"[1]) is a disorder of pigmentation that develops within a few weeks of birth and progresses for one to two years before stabilizing.[2]: 549  There is linear and whorled hyperpigmentation following the lines of Blaschko without preceding bullae or verrucous lesions.[2]: 549  It is important to exclude other pigmentary disorders following the Blaschko lines before making a diagnosis of linear and whorled nevoid hypermelanosis. The differential diagnoses include incontinentia pigmenti, linear epidermal nevus, hypomelanosis of Ito and Goltz syndrome. Recently, a case of linear and whorled nevoid hypermelanosis was reported in a Malaysian Chinese girl.[3]

See also


  1. Bolognia, Jean L.; et al. (2007). Dermatology. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
  2. 2.0 2.1 James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
  3. Yap FBB. Linear and whorled nevoid hypermelanosis in a Malaysian Chinese girl Archived 2015-03-06 at the Wayback Machine. Egyptian Dermatology Online Journal 2008; 4(2).

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