Landolfi's sign

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Landolfi's sign
SymptomsConstricting pupils with each heart beat[1]

Landolfi's sign is the alternating constriction and dilatation of pupils seen in aortic regurgitation; it appears as constricting pupils with each heart beat.[1]


  1. 1.0 1.1 Ghosh, Ritwik; Sengupta, Swagatam; Siraj, SK Minhajuddin; Benito-León, Julián (2020). "Landolfi's Sign: A Riddle for Primary Care Physicians". Journal of primary care specialties : official publication of the Institute of Family Medicine and Primary Care. 1 (1): 13–14. doi:10.4103/jopcs.jopcs_14_20. ISSN 2772-3615. PMID 35865711. Archived from the original on 2022-09-02. Retrieved 2022-11-07.

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