Kimmie Ng

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Kimmie Ng

Kimmie Ng

Kimmie Ng is a physician at Dana–Farber Cancer Institute who is known for her work on colorectal cancer in young patients.

Education and career

Ng has an undergraduate degree from Yale University (1997) and earned her M.D. from the University of Pennsylvania in 2001. Subsequently she trained at the University of California, San Francisco and Dana–Farber Cancer Institute. In 2007, she received a masters in public health from Harvard University.[1][2] As of 2021, Ng is a physician at the Dana–Farber Cancer Institute and a professor at Harvard Medical School.[3] Ng is the director of Dana-Farber's Young-Onset Colorectal Cancer Center.[3]

Research

Ng is known for her work in gastrointestinal cancer, with a particular focus in addressing the rise in colorectal cancer in people under the age of fifty. In college, Ng focused on laboratory-based research in biochemistry.[4][5] She shifted her focus to medicine where her research has shown increased survival in colorectal cancer patients following the consumption of vitamin D,[6][7] research that has been widely covered by the media.[8] She has also written about the survival rates in young patients with colorectal cancer.[9][10] Ng has advocated for lowering the age of screening for colorectal cancer,[11] and has spoken in multiple venues about the need to increase colorectal cancer screening for younger people.[12][13][14][15] Ng also investigates the role of diet and microbiome in colorectal cancer,[16] including one project that examined coffee intake by colorectal patients.[17][18] Ng leads a 2021 research project that uses social media to connect with colorectal cancer patients.[19] Ng has spoken about the impact of the COVID-19 pandemic on her personal life,[20] and how the pandemic impacts treatment and diagnoses for cancer patients.[21][22]

Selected publications

  • Bullman, Susan; Pedamallu, Chandra S.; Sicinska, Ewa; Clancy, Thomas E.; Zhang, Xiaoyang; Cai, Diana; Neuberg, Donna; Huang, Katherine; Guevara, Fatima; Nelson, Timothy; Chipashvili, Otari (2017-12-15). "Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer". Science. 358 (6369): 1443–1448. Bibcode:2017Sci...358.1443B. doi:10.1126/science.aal5240. ISSN 0036-8075. PMC 5823247. PMID 29170280.
  • Ng, Kimmie; Meyerhardt, Jeffrey A.; Wu, Kana; Feskanich, Diane; Hollis, Bruce W.; Giovannucci, Edward L.; Fuchs, Charles S. (2008-06-20). "Circulating 25-Hydroxyvitamin D Levels and Survival in Patients With Colorectal Cancer". Journal of Clinical Oncology. 26 (18): 2984–2991. doi:10.1200/JCO.2007.15.1027. ISSN 0732-183X. PMID 18565885.
  • Ng, K; Wolpin, B M; Meyerhardt, J A; Wu, K; Chan, A T; Hollis, B W; Giovannucci, E L; Stampfer, M J; Willett, W C; Fuchs, C S (2009-09-15). "Prospective study of predictors of vitamin D status and survival in patients with colorectal cancer". British Journal of Cancer. 101 (6): 916–923. doi:10.1038/sj.bjc.6605262. ISSN 0007-0920. PMC 743349. PMID 19690551.
  • Ng, Kimmie; Meyerhardt, Jeffrey A.; Chan, Andrew T.; Sato, Kaori; Chan, Jennifer A.; Niedzwiecki, Donna; Saltz, Leonard B.; Mayer, Robert J.; Benson, Al B.; Schaefer, Paul L.; Whittom, Renaud (2015). "Aspirin and COX-2 Inhibitor Use in Patients With Stage III Colon Cancer". JNCI: Journal of the National Cancer Institute. 107 (1): 345. doi:10.1093/jnci/dju345. ISSN 1460-2105. PMC 4271076. PMID 25432409.
  • Ng, Kimmie; Nimeiri, Halla S.; McCleary, Nadine J.; Abrams, Thomas A.; Yurgelun, Matthew B.; Cleary, James M.; Rubinson, Douglas A.; Schrag, Deborah; Miksad, Rebecca; Bullock, Andrea J.; Allen, Jill (2019-04-09). "Effect of High-Dose vs Standard-Dose Vitamin D 3 Supplementation on Progression-Free Survival Among Patients With Advanced or Metastatic Colorectal Cancer: The SUNSHINE Randomized Clinical Trial". JAMA. 321 (14): 1370–1379. doi:10.1001/jama.2019.2402. ISSN 0098-7484. PMC 6459117. PMID 30964527.

Awards and honors

In 2020, Ng received a young investigator award from Conquer Cancer, a foundation run by the American Society of Clinical Oncology.[23]

References

  1. ^ "Kimmie Ng, MD, MPH - Dana-Farber Cancer Institute | Boston, MA". www.dana-farber.org. Retrieved 2021-12-25.
  2. ^ "Kimmie Ng - Director , Assistant Professor of Oncology in Boston, Massachusetts, United States of America | eMedEvents". eMedEvents.com. Retrieved 2021-12-29.
  3. ^ a b "Kimmie Ng, MD, MPH - Dana-Farber Cancer Institute | Boston, MA". www.dana-farber.org. Retrieved 2021-12-29.
  4. ^ "Colorectal Cancer Expert: Dr. Kimmie Ng, Gastrointestinal Oncologist | The Patient Story - The Patient Story". The Patient Story | For Cancer Patients & Caregivers. 2021-01-19. Retrieved 2021-12-29.
  5. ^ Astatke, Mekbib; Ng, Kimmie; Grindley, Nigel D. F.; Joyce, Catherine M. (1998-03-31). "A single side chain prevents Escherichia coli DNA polymerase I (Klenow fragment) from incorporating ribonucleotides". Proceedings of the National Academy of Sciences. 95 (7): 3402–3407. Bibcode:1998PNAS...95.3402A. doi:10.1073/pnas.95.7.3402. ISSN 0027-8424. PMC 19848. PMID 9520378.
  6. ^ Ng, Kimmie; Nimeiri, Halla S.; McCleary, Nadine J.; Abrams, Thomas A.; Yurgelun, Matthew B.; Cleary, James M.; Rubinson, Douglas A.; Schrag, Deborah; Miksad, Rebecca; Bullock, Andrea J.; Allen, Jill (2019-04-09). "Effect of High-Dose vs Standard-Dose Vitamin D 3 Supplementation on Progression-Free Survival Among Patients With Advanced or Metastatic Colorectal Cancer: The SUNSHINE Randomized Clinical Trial". JAMA. 321 (14): 1370–1379. doi:10.1001/jama.2019.2402. ISSN 0098-7484. PMC 6459117. PMID 30964527.
  7. ^ Ng, Kimmie; Meyerhardt, Jeffrey A.; Wu, Kana; Feskanich, Diane; Hollis, Bruce W.; Giovannucci, Edward L.; Fuchs, Charles S. (2008-06-20). "Circulating 25-Hydroxyvitamin D Levels and Survival in Patients With Colorectal Cancer". Journal of Clinical Oncology. 26 (18): 2984–2991. doi:10.1200/JCO.2007.15.1027. ISSN 0732-183X. PMID 18565885.
  8. ^ Forster, Victoria. "Vitamin D May Help To Prevent Colorectal Cancer In Young People". Forbes. Retrieved 2021-12-29.
  9. ^ Rauf, Don (October 28, 2021). "Young Adults With Colorectal Cancer Survive No Longer Than Older Patients". EverydayHealth.com. Retrieved 2021-12-25.
  10. ^ Lipsyc-Sharf, Marla; Zhang, Sui; Ou, Fang-Shu; Ma, Chao; McCleary, Nadine Jackson; Niedzwiecki, Donna; Chang, I-Wen; Lenz, Heinz-Josef; Blanke, Charles D; Piawah, Sorbarikor; Van Loon, Katherine (2021-10-12). "Survival in Young-Onset Metastatic Colorectal Cancer: Findings From Cancer and Leukemia Group B (Alliance)/SWOG 80405". JNCI: Journal of the National Cancer Institute. 114 (3): 427–435. doi:10.1093/jnci/djab200. ISSN 0027-8874. PMC 8902338. PMID 34636852.
  11. ^ Ng, Kimmie; May, Folasade P.; Schrag, Deborah (2021-05-18). "US Preventive Services Task Force Recommendations for Colorectal Cancer Screening: Forty-Five Is the New Fifty". JAMA. 325 (19): 1943–1945. doi:10.1001/jama.2021.4133. ISSN 0098-7484. PMID 34003238. S2CID 234768751.
  12. ^ Jacqueline Howard (27 October 2020). "US task force proposes starting colorectal cancer screening at age 45". CNN. Retrieved 2021-12-29.
  13. ^ "CityLine: Sun. Aril 18, 2021: Dr. Kimmie Ng". WCVB. 2021-04-18. Retrieved 2021-12-29.
  14. ^ Rabin, Roni Caryn (2020-10-27). "Colon Cancer Screening Should Start Earlier, at Age 45, U.S. Panel Says". The New York Times. ISSN 0362-4331. Retrieved 2021-12-29.
  15. ^ Mascia, Kristen (2020-08-29). "Why Are Young Guys Suddenly Getting Colon Cancer?". Men's Health. Retrieved 2021-12-29.
  16. ^ Willyard, Cassandra (December 1, 2021). "The Colon Cancer Conundrum". Scientific American.
  17. ^ Mackintosh, Christopher; Yuan, Chen; Ou, Fang-Shu; Zhang, Sui; Niedzwiecki, Donna; Chang, I-Wen; O’Neil, Bert H.; Mullen, Brian C.; Lenz, Heinz-Josef; Blanke, Charles D.; Venook, Alan P. (2020-11-01). "Association of Coffee Intake With Survival in Patients With Advanced or Metastatic Colorectal Cancer". JAMA Oncology. 6 (11): 1713–1721. doi:10.1001/jamaoncol.2020.3938. ISSN 2374-2437. PMC 7499248. PMID 32940631.
  18. ^ Landsverk, Gabby (September 28, 2020). "Drinking up to 4 cups of coffee a day may improve outcomes for colon cancer patients, even if it's decaf". Insider. Retrieved 2021-12-29.
  19. ^ "Dana Farber Cancer Institute Launches Colorectal Cancer Project That Uses Social Media". Retrieved 2021-12-29.
  20. ^ Rivera, Sofia (April 24, 2020). "Hotels, In-Law Apartments, and Basements: How Doctors Are Quarantining during the COVID-19 Pandemic". Boston. Retrieved December 29, 2021.
  21. ^ Edwards, Erika (June 19, 2020). "The COVID-19 pandemic may have an unexpected impact: A dramatic increase in cancer deaths". NBC News. Retrieved 2021-12-29.
  22. ^ Weintraub, Karen. "'I'm smiling under here': Masks, plexiglass and questions the norm as hospitals lure patients back in COVID-19 era". USA TODAY. Retrieved 2021-12-29.
  23. ^ "Addressing the Disturbing Rise of Young-Onset Colorectal Cancer". ASCO Daily News. March 11, 2020. Retrieved 2021-12-29.
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