Karine Auclair

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Karine Auclair
Alma materUniversity of Alberta
Scientific career
InstitutionsMcGill University
ThesisBiosynthetic studies on the polyketide lovastatin : enzyme-catalyzed diels-alder reactions (1999)
Doctoral advisorJohn C. Vederas

Karine Auclair is a professor of chemistry at McGill University in Montréal, Canada.[1] She is the current Canada Research Chair in Antimicrobials and Green Enzymes.[1][2]

Education and career

Auclair completed a Bachelor of Science in chemistry at Université du Québec à Chicoutimi in 1994, followed by a Doctor of Philosophy (Ph.D.) in organic chemistry at the University of Alberta in 1999.[1][3] She then completed a post-doctoral fellowship in pharmaceutical chemistry at the University of California, San Francisco from 1999 to 2001.[1][3]

Auclair began her teaching and research career at McGill University in 2002 as an assistant professor of chemistry.[1][3] She has been a full professor since 2016.[1][3]

Selected publications

  • Kennedy, Jonathan; Auclair, Karine; Kendrew, Steven G.; Park, Cheonseok; Vederas, John C.; Hutchinson, C. Richard (21 May 1999). "Modulation of Polyketide Synthase Activity by Accessory Proteins During Lovastatin Biosynthesis". Science. 284 (5418): 1368–1372. Bibcode:1999Sci...284.1368K. doi:10.1126/science.284.5418.1368. PMID 10334994.
  • Auclair, Karine; Sutherland, Andrew; Kennedy, Jonathan; Witter, David J.; Van den Heever, Johan P.; Hutchinson, C. Richard; Vederas, John C. (22 November 2000). "Lovastatin Nonaketide Synthase Catalyzes an Intramolecular Diels−Alder Reaction of a Substrate Analogue". Journal of the American Chemical Society. 122 (46): 11519–11520. doi:10.1021/ja003216+.
  • Auclair, Karine; Hu, Zhengbo; Little, Dorothy M.; Ortiz de Montellano, Paul R.; Groves, John T. (May 2002). "Revisiting the Mechanism of P450 Enzymes with the Radical Clocks Norcarane and Spiro[2,5]octane". Journal of the American Chemical Society. 124 (21): 6020–6027. doi:10.1021/ja025608h. PMID 12022835.

References

  1. ^ a b c d e f "Karine Auclair". Department of Chemistry. McGill University. Retrieved 4 April 2021.
  2. ^ "Tier 1 Canada Research Chairs". Office of the Provost and Vice-Principal (Academic). McGill University. Retrieved 4 April 2021.
  3. ^ a b c d "Prof. Karine Auclair". Auclair Lab. McGill University. Retrieved 4 April 2021.