KRT75

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keratin 75
Identifiers
SymbolKRT75
NCBI gene9119
HGNC24431
RefSeqNM_004693
Other data
LocusChr. 12 q13

KRT75 is a keratin gene involved in hair shaft structure in mice.[1] In chickens, mutations in KRT75 cause animals to have frizzled feathers.[2]

References

  1. ^ Liu Y, Snedecor ER, Zhang X, Xu Y, Huang L, Jones EC, Zhang L, Clark RA, Roop DR, Qin C, Chen J (January 2016). "Correction of Hair Shaft Defects through Allele-Specific Silencing of Mutant Krt75". The Journal of Investigative Dermatology. 136 (1): 45–51. doi:10.1038/JID.2015.375. PMC 4764097. PMID 26763422.
  2. ^ Ng CS, Wu P, Foley J, Foley A, McDonald ML, Juan WT, Huang CJ, Lai YT, Lo WS, Chen CF, Leal SM, Zhang H, Widelitz RB, Patel PI, Li WH, Chuong CM (2012). "The chicken frizzle feather is due to an α-keratin (KRT75) mutation that causes a defective rachis". PLOS Genetics. 8 (7): e1002748. doi:10.1371/journal.pgen.1002748. PMC 3400578. PMID 22829773.