KRT36

From WikiProjectMed
Jump to navigation Jump to search
KRT36
Identifiers
AliasesKRT36, HA6, KRTHA6, hHa6, keratin 36
External IDsOMIM: 604540 MGI: 109364 HomoloGene: 88459 GeneCards: KRT36
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003771

NM_001174099
NM_008472

RefSeq (protein)

NP_003762

NP_001167570

Location (UCSC)Chr 17: 41.49 – 41.49 MbChr 11: 99.99 – 100 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Keratin, type I cuticular Ha6 is a protein that in humans is encoded by the KRT36 gene.[5][6][7]

The protein encoded by this gene is a member of the keratin gene family. This type I hair keratin is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription.[7]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000126337 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020916 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Rogers MA, Winter H, Wolf C, Heck M, Schweizer J (Nov 1998). "Characterization of a 190-kilobase pair domain of human type I hair keratin genes". J Biol Chem. 273 (41): 26683–91. doi:10.1074/jbc.273.41.26683. PMID 9756910.
  6. ^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins". J Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.
  7. ^ a b "Entrez Gene: KRT36 keratin 36".

Further reading