Infantile acropustulosis

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Infantile acropustulosis
Other names: Acropustulosis of infancy[1]: 483 )
SymptomsIntensely itchy small blisters on hands and feet of infants[2]
Risk factorsScabies[2]
TreatmentApplying corticosteroid[2]
PrognosisResolves within 2-years[3]
FrequencyUncommon, first 6-months of life[3]

Infantile acropustulosis is an intensely itchy blistering eruption of the hands and feet of babies.[2] It typically appears in crops as small red bumps, which over 24-hours become small clear blisters and then small yellow blisters.[3] They last around 7 to 14 days with new crops appearing every 2 to 4 weeks.[3] Scratching them results in sores and crusting.[3]

There may be a history of preceding scabies, which may reflect an allergic reaction to scabies.[3] How it occurs is unclear.[4]

Applying corticosteroid may help.[2] If that fails then dapsone at 1-2mg/kg/day may be considered.[2] They heal with temporary scarring.[3] The condition tends to get within 2-years.[3]

The condition typically occurs in the first 6-months of life, but is uncommon.[3] The condition was described in 1979.[4]

Signs and symptoms

See also


  1. Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
  2. 2.0 2.1 2.2 2.3 2.4 2.5 James, William D.; Elston, Dirk; Treat, James R.; Rosenbach, Misha A.; Neuhaus, Isaac (2020). "10. Seborrheic dermatitis, psoriasis, recalcitrant palmopustular eruptions, pustular dermatitis, and erythroderma". Andrews' Diseases of the Skin: Clinical Dermatology (13th ed.). Edinburgh: Elsevier. pp. 203–204. ISBN 978-0-323-54753-6. Archived from the original on 2022-06-04. Retrieved 2022-06-02.
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 3.8 "Acropustulosis of infancy". Primary Care Dermatology Society. Archived from the original on 1 February 2020. Retrieved 2 June 2022.
  4. 4.0 4.1 Ellison, Cassondra A (5 March 2020). "Acropustulosis of Infancy: Background, Pathophysiology, Etiology". Archived from the original on 13 June 2021. Retrieved 2 June 2022.

External links

External resources