|Pronunciation||hoe mat' roe peen|
|Trade names||Equipin, Isopto Homatropine|
|Other names||Homatropine hydrobromide|
|Main uses||Dilate the pupil|
|Side effects||Increased eye pressure, stinging, sensitivity to light, dry mouth|
|Duration of action||Up to 4 days|
|Chemical and physical data|
|Molar mass||275.348 g·mol−1|
|3D model (JSmol)|
Homatropine, sold under the brand name Homatropaire among others, is a medication used to dilate the pupil as part of an eye exam or to help with the pain of anterior uveitis. It is used as an eye drop. Effects begin within 10 minutes and may last for up to 4 days.
Homatropine was first made in 1883 or 1884. It is available as a generic medication. It is on the World Health Organization's List of Essential Medicines as an alternative to atropine. In the United States a 5 ml bottle costs about 40 USD as of 2021. It is made from atropine.
Homatropine is less potent than atropine and has a shorter duration of action. It is available as the hydrobromide salt. Homatropine is also given as an atropine substitute given to reverse the muscarinic and CNS effects associated with indirect cholinomimetic (anti-AChase) administration.
The related chemical compound homatropine methylbromide (methylhomatropine) is a different medication.
- Blurred vision
- Sensitivity to light
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