HLA-B54
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major histocompatibility complex (human), class I, B54
| ||
| Alleles | B*5401 | |
| Structure (See HLA-B) | ||
| Symbol(s) | HLA-B | |
| EBI-HLA | B*5401 | |
| Locus | chr.6 6p21.31 | |
HLA-B54 (B54) is an HLA-B serotype. B54 is a split antigen from the B22 broad antigen, sister serotypes are B55 and B56.[1] The serotype identifies the more common HLA-B*55 gene products.[2]
Serotype
| B*54 | B54 | B22 | Sample |
| allele | % | % | size (N) |
| 5401 | 67 | 3 | 631 |
Allele distribution
| freq | ||
| ref. | Population | (%) |
| [4] | USA Hawaii Okinawa | 10.6 |
| [4] | Japan Central | 7.7 |
| [4] | South Korea (3) | 5.9 |
| [4] | China Guangzhou | 4.5 |
| [4] | Thailand (3) | 4.1 |
| [4] | China Inner Mongolia | 3.4 |
| [4] | China North Han | 3.3 |
| [4] | China Beijing Shijiazhuang Tianjian Han | 3.0 |
| [4] | China South Han | 2.5 |
| [4] | Russia Tuva pop 2 | 2.2 |
| [4] | China Guangxi Maonan | 1.9 |
| [4] | Thailand | 1.8 |
| [4] | Taiwan Thao | 1.7 |
| [4] | China Tibet Autonomous Region Tibetans | 1.3 |
See also
References
- ^ Hildebrand, W. H.; Madrigal, J. A.; Little, A. M.; Parham, P. (1992). "HLA-Bw22: a family of molecules with identity to HLA-B7 in the alpha 1-helix". Journal of Immunology. 148 (4): 1155–1162. PMID 1737933.
- ^ Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
- ^ derived from IMGT/HLA
- ^ a b c d e f g h i j k l m n Middleton, D.; Menchaca, L.; Rood, H.; Komerofsky, R. (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–407. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.