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Combination of
HydrochlorothiazideThiazide diuretic
OlmesartanAngiotension receptor blocker
Trade namesBenicar HCT, Benitec H, others
Clinical data
Routes of
By mouth
Defined daily dosenot established[1]
Legal status
  • In general: ℞ (Prescription only)

Olmesartan/hydrochlorothiazide, sold under the brand name Benicar HCT among others, is a medication used to treat high blood pressure.[2] It is a combination of olmesartan, an angiotension receptor blocker and hydrochlorothiazide, a diuretic.[2] It may be used if olmesartan is not sufficient to manage blood pressure.[3] It is taken by mouth.[3]

Common side effects include nausea, dizziness, and upper respiratory tract infections.[4] Serious side effects may include kidney problems, allergic reactions, electrolyte problems and low blood pressure.[4] Use in pregnancy is not recommended.[4] Olmesartan works by blocking the effects of angiotensin II while hydrochlorothiazide works by increasing the loss of sodium by the kidneys.[4]

No generic version is available in the United States as of 2017.[2] A month supply in the United Kingdom costs the NHS about 13 £ as of 2019.[3] In the United States the wholesale cost of this amount is about US$6.[5] In 2017, it was the 292nd most commonly prescribed medication in the United States, with more than one million prescriptions.[6][7]


The defined daily dose is not established[1]


  1. 1.0 1.1 "WHOCC - ATC/DDD Index". www.whocc.no. Retrieved 10 September 2020.
  2. 2.0 2.1 2.2 Bope, Edward T.; Kellerman, Rick D. (2016). Conn's Current Therapy 2017 E-Book. Elsevier Health Sciences. p. 124. ISBN 9780323443357.
  3. 3.0 3.1 3.2 British national formulary : BNF 76 (76 ed.). Pharmaceutical Press. 2018. pp. 177–178. ISBN 9780857113382.
  4. 4.0 4.1 4.2 4.3 "Olmesartan Medoxomil and Hydrochlorothiazide - FDA prescribing information, side effects and uses". Drugs.com. Retrieved 11 March 2019.
  5. "NADAC as of 2019-02-27". Centers for Medicare and Medicaid Services. Retrieved 3 March 2019.
  6. "The Top 300 of 2020". ClinCalc. Retrieved 11 April 2020.
  7. "Hydrochlorothiazide; Olmesartan Medoxomil - Drug Usage Statistics". ClinCalc. Retrieved 11 April 2020.

External links