Guanosine deaminase

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guanosine deaminase
Identifiers
EC no.3.5.4.15
CAS no.9067-85-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a guanosine deaminase (EC 3.5.4.15) is an enzyme that catalyzes the chemical reaction

guanosine + H2O xanthosine + NH3

Thus, the two substrates of this enzyme are guanosine and H2O, whereas its two products are xanthosine and NH3.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is guanosine aminohydrolase. This enzyme is also called guanosine aminase.

References

  • Isihida Y, Shirafiji H, Kida M, Yoneda M (1969). "Studies on the guanosine degrading system in bacterial cell. III Preparation and properties of guanosine deaminase". Agric. Biol. Chem. 33: 384–390. doi:10.1080/00021369.1969.10859324.