Glucose-1-phosphatase
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| glucose-1-phosphatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.3.10 | ||||||||
| CAS no. | 9001-38-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme glucose-1-phosphatase (EC 3.1.3.10) catalyzes the reaction
- α-D-glucose 1-phosphate + H2O D-glucose + phosphate
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name is α-D-glucose-1-phosphate phosphohydrolase. This enzyme participates in glycolysis and gluconeogenesis.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1NT4.
References
- Faulkner P (August 1955). "A hexose-1-phosphatase in silkworm blood". The Biochemical Journal. 60 (4): 590–6. doi:10.1042/bj0600590. PMC 1216157. PMID 13249953.
- Turner DH, Turner JF (March 1960). "The hydrolysis of glucose monophosphates by a phosphatase preparation from pea seeds". The Biochemical Journal. 74 (3): 486–91. doi:10.1042/bj0740486. PMC 1204246. PMID 13839934.
