Generalized vaccinia

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Generalized vaccinia
Generalized vaccinia -Pustular lesion on individuals shoulder, 6 days after revaccination.
SpecialtyDermatology, infectious diseases
SymptomsClusters of small blisters[1]
TreatmentUsually none,[2] vaccinia immune globulin intravenous (VIGIV)[3]

Generalized vaccinia is an eruption of vaccinia 6–9 days after vaccination, presenting as clusters of small blisters on a red base.[1][2]

It may be treated with Vaccinia immune globulin intravenous (VIGIV).[3]

It occurred in around 242 of every million smallpox vaccines.[4]

See also


  1. 1.0 1.1 James, William D.; Elston, Dirk; Treat, James R.; Rosenbach, Misha A.; Neuhaus, Isaac (2020). "19. Viral diseases". Andrews' Diseases of the Skin: Clinical Dermatology (13th ed.). Edinburgh: Elsevier. pp. 387–388. ISBN 978-0-323-54753-6. Archived from the original on 2023-07-01. Retrieved 2023-06-06.
  2. 2.0 2.1 "Smallpox Vaccination and Adverse Reactions". Archived from the original on 2021-03-20. Retrieved 2022-05-30.
  3. 3.0 3.1 "Medical Management of Adverse Reactions to Vaccinia Virus Vaccination | Smallpox | CDC". 2 November 2021. Archived from the original on 20 May 2022. Retrieved 30 May 2022.
  4. Petersen, Brett W.; Damon, Inger K. (2020). "348. Smallpox, monkeypox and other poxvirus infections". In Goldman, Lee; Schafer, Andrew I. (eds.). Goldman-Cecil Medicine. Vol. 2 (26th ed.). Philadelphia: Elsevier. p. 2183. ISBN 978-0-323-53266-2. Archived from the original on 2023-07-01. Retrieved 2023-06-06.