GPR22

GPR22
Identifiers
Aliases	GPR22, G protein-coupled receptor 22
External IDs	OMIM: 601910 MGI: 1920260 HomoloGene: 18420 GeneCards: GPR22
Gene location (Human)
Chr.	Chromosome 7 (human)
End	107,475,684 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	31,763,946 bp
RNA expression pattern
	Top expressed in
	superior frontal gyrus; ; prefrontal cortex; ; dorsolateral prefrontal cortex; ; Brodmann area 9; ; left ventricle; ; hippocampus proper; ; corpus callosum; ; cerebellar cortex; ; cerebellar hemisphere; ; amygdala;
	Top expressed in
	subiculum; ; interventricular septum; ; Region I of hippocampus proper; ; hippocampus proper; ; dentate gyrus; ; cerebellar vermis; ; primary motor cortex; ; piriform cortex; ; superior cervical ganglion; ; visual cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	peptide binding; signal transducer activity; G protein-coupled receptor activity;
Cellular component	integral component of membrane; plasma membrane; membrane; integral component of plasma membrane;
Biological process	cellular response to hormone stimulus; signal transduction; response to peptide; G protein-coupled receptor signaling pathway; cell projection organization;
	Sources:Amigo / QuickGO
Orthologs
	2845
	73010
	ENSG00000172209; ENSG00000283812
	ENSMUSG00000044067
	Q99680; Q3KNS9
	Q8BZL4
	NM_005295
	NM_175191
	NP_005286; NP_005286.2
	NP_780400
	Wikidata
View/Edit Human	View/Edit Mouse

Probable G-protein coupled receptor 22 is a protein that in humans is encoded by the GPR22 gene.^[5]^[6]

References

^ ^a ^b ^c ENSG00000283812 GRCh38: Ensembl release 89: ENSG00000172209, ENSG00000283812 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000044067 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ O'Dowd BF, Nguyen T, Jung BP, Marchese A, Cheng R, Heng HH, Kolakowski LF Jr, Lynch KR, George SR (Apr 1997). "Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes". Gene. 187 (1): 75–81. doi:10.1016/S0378-1119(96)00722-6. PMID 9073069.
^ "Entrez Gene: GPR22 G protein-coupled receptor 22".

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. Bibcode:2003Natur.424..157H. doi:10.1038/nature01782. PMID 12853948.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Lee J, Hever A, Willhite D, et al. (2006). "Effects of RNA degradation on gene expression analysis of human postmortem tissues". FASEB J. 19 (10): 1356–8. doi:10.1096/fj.04-3552fje. PMID 15955843. S2CID 3200625.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.

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