Flotufolastat F-18
![]() Flotufolastat F-18 gallium | |
Names | |
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Trade names | Posluma |
Other names | 18F-rhPSMA-7.3 |
Clinical data | |
Drug class | Radioactive diagnostic agent |
Main uses | PET imaging of prostate cancer[1] |
Side effects | Diarrhea, high blood pressure, pain at site of injection[1] |
Routes of use | Intravenous |
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Flotufolastat F-18, sold under the brand name Posluma, is a radioactive diagnostic agent used in positron emission tomography (PET) imaging of prostate cancer.[1] Specifically it is used in prostate-specific membrane antigen (PSMA) positive disease to look for spread or recurrence.[1] It is given by injection into a vein.[1]
Common side effects include diarrhea, high blood pressure, and pain at the site of injection.[1] Other side effects include exposure to radiation.[1] The active ingredient is flotufolastat F-18 gallium.[1]
Flotufolastat F-18 was approved for medical use in the United States in 2023.[1]
Medical uses
Flotufolastat F-18 is indicated for positron emission tomography of prostate-specific membrane antigen positive lesions in men with prostate cancer.[1]
References
External links
Identifiers: |
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- Clinical trial number NCT04186819 for "Imaging Study to Investigate the Safety and Diagnostic Performance of rhPSMA 7.3 (18F) in Newly Diagnosed Prostate Cancer (LIGHTHOUSE)" at ClinicalTrials.gov
- Clinical trial number NCT04186845 for "Imaging Study to Investigate Safety and Diagnostic Performance of rhPSMA 7.3 (18F) PET Ligand in Suspected Prostate Cancer Recurrence (SPOTLIGHT)" at ClinicalTrials.gov
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