File:PMC5034810 ANA-78-272-g004.png

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Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)

Summary

Author:Chi‐Chao Chao, Cho‐Min Huang, Hao‐Hua Chiang, Kai‐Ren Luo, Hung‐Wei Kan, Naomi Chu‐Chiao Yang, Hao Chiang, Whei‐Min Lin, Shu‐Mei Lai, Ming‐Jen Lee, Chia‐Tung Shun, Sung‐Tsang Hsieh,Department of Neurology, National Taiwan University Hospital,Department of Anatomy and Cell Biology, National Taiwan University College of Medicine,Department of Pathology, National Taiwan University Hospital,Department of Forensic Medicine,Graduate Institute of Brain and Mind Sciences,Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine(Openi/National Library of Medicine) Source:https://openi.nlm.nih.gov/detailedresult?img=PMC5034810_ANA-78-272-g004&query=Familial%20amyloid%20polyneuropathy&it=xg&req=4&npos=6 Description:ana24438-fig-0004: Sweat gland innervations in familial amyloid polyneuropathy (FAP). Skin sections were immunostained with protein gene product 9.5 (PGP 9.5) antiserum and then counterstained with Congo red. (A) In the control skin, sweat glands appeared as red coils and were surrounded by the linear and varicose sudomotor nerve fibers of dense PGP 9.5 immunoreactivities. (B) The sweat gland innervation was markedly reduced in FAP, and only some scattered and fragmented immunoreactivities surrounding a small portion of the sweat gland could be observed, indicating sudomotor nerve degeneration. Scale bar = 50μm.