File:PMC5022363 fped-04-00098-g001.png

License

Attribution 4.0 International (CC BY 4.0)

Summary

Author:Shahrzad Bakhtiar, Frank Ruemmele, Fabienne Charbit-Henrion, Eva Lévy, Frédéric Rieux-Laucat, Nadine Cerf-Bensussan, Peter Bader, Ulrich Paetow,Division for Pediatric Stem Cell Transplantation and Immunology, University Hospital Frankfurt, UMR 1163, Laboratory of Intestinal Immunity, INSERM, Université Paris Descartes-Sorbonne Paris Cité and Institut Imagine,GENIUS Group (GENetically ImmUne mediated enteropathieS) from ESPGHAN (European Society for Pediatric Gastroenterology, Hepatology and Nutrition), Department of Pediatric Gastroenterology, Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Laboratory of Immunogenetics of Pediatric Autoimmune Diseases, INSERM, Division for Pediatric Endocrinology, University Hospital Frankfurt(Openi/National Library of Medicine)Source:https://openi.nlm.nih.gov/detailedresult?img=PMC5022363_fped-04-00098-g001&query=LRBA%20deficiency&it=xg&req=4&npos=2 Description:F1: (A) Chest CT-scan of Patient 1 showing severe polyserositis with pleural and pericardial effusions; (B) patient 2 with progressive perioral vitiligo without other abnormalities in her face; and (C) ultrasound of the thyroid gland in Patient 2 showing a hypotrophic thyroid gland with 2.5 ml volume and several nodules <5 mm.