File:PMC4698281 401 2015 1515 Fig6 HTML.png

License

Attribution 4.0 International (CC BY 4.0)

Summary

Author:McKee AC, Cairns NJ, Dickson DW, Folkerth RD, Keene CD, Litvan I, Perl DP, Stein TD, Vonsattel JP, Stewart W, Tripodis Y, Crary JF, Bieniek KF, Dams-O'Connor K, Alvarez VE, Gordon WA, Department of Neurology, Boston University School of Medicine (Openi/National Library of Medicine) Source:https://openi.nlm.nih.gov/detailedresult?img=PMC4698281_401_2015_1515_Fig6_HTML&query=Chronic%20traumatic%20encephalopathy&it=xg&req=4&npos=53 Description:Fig6: Minimum recommended brain regions for evaluation for CTE. The following sections from the NIA-AA blocking scheme are recommended for p-tau immunostaining in evaluation for CTE (blue rectangles). In the cortical sections (blocks 1–5, 12, 13), the depths of the cortical sulci should be included in the section. 1 Middle frontal gyrus, 2 superior and middle temporal gyri, 3 inferior parietal lobule, 4 hippocampus, 5 amygdala and entorhinal cortex, 6 basal ganglia at level of anterior commissure with basal nucleus of Meynert, 7 thalamus, 8 midbrain with substantia nigra, 9 pons with locus coeruleus, 10 medulla oblongata, 11 cerebellar cortex and dentate nucleus; additional sections if high suspicion of CTE (red rectangles): 12 superior frontal gyrus, 13 temporal pole, 14 hypothalamus and mammillary body