File:ONSR.Filoviridae.Fig3.v5.png
Jump to navigation
Jump to search
Size of this preview: 800 × 413 pixels. Other resolutions: 320 × 165 pixels | 640 × 330 pixels | 1,024 × 528 pixels | 1,280 × 661 pixels | 3,321 × 1,714 pixels.
Original file (3,321 × 1,714 pixels, file size: 272 KB, MIME type: image/png)
Summary
| Description |
English: Replication cycle of filoviruses (possibly excluding striaviruses and thamnoviruses). Virions attach to cell-surface attachment factors (orange Ys) and are taken into the cell via endocytosis. The filovirion glycoproteins (yellow clubs) bind to endosomal Niemann-Pick disease, type C1 (NPC1, white zigzag) catalyze the fusion of viral and cellular membranes to release the filovirus RNP complex (green helix). The polymerase complex (consisting of VP35 [purple dots] and L [blue semicircles]) transcribes filovirus mRNAs that are translated into filovirus proteins and replicates filovirus genomic RNA via antigenomic intermediates. Genomic RNA and antigenomic RNA occur only as ribonucleoprotein complexes which serve as templates for replication and/or transcription. Assembly of filoviral proteins and progeny genomes occurs in the cytoplasm and results in budding of progeny virions at the plasma membrane. |
| Date | |
| Source | https://talk.ictvonline.org/ictv-reports/ictv_online_report/negative-sense-rna-viruses/mononegavirales/w/filoviridae |
| Author |
Source authors: Jens H. Kuhn, Gaya K. Amarasinghe, Christopher F. Basler, Sina Bavari, Alexander Bukreyev, Kartik Chandran, Ian Crozier, Olga Dolnik, John M. Dye, Pierre B. H. Formenty, Anthony Griffiths, Roger Hewson, Gary P. Kobinger, Eric M. Leroy, Elke Mühlberger, Sergey V. Netesov (Нетёсов Сергей Викторович), Gustavo Palacios, Bernadett Pályi, Janusz T. Pawęska, Sophie J. Smither, Ayato Takada (高田礼人), Jonathan S. Towner and Victoria Wahl Image courtesy of: Jiro Wada, IRF-Frederick, Fort Detrick, MD, USA. (US government) |
Licensing
This file is licensed under the Creative Commons Attribution 4.0 International license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
File history
Click on a date/time to view the file as it appeared at that time.
| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 11:14, 10 September 2020 | | 3,321 × 1,714 (272 KB) | commons>Guest2625 | Uploaded a work by Source authors: Jens H. Kuhn, Gaya K. Amarasinghe, Christopher F. Basler, Sina Bavari, Alexander Bukreyev, Kartik Chandran, Ian Crozier, Olga Dolnik, John M. Dye, Pierre B. H. Formenty, Anthony Griffiths, Roger Hewson, Gary P. Kobinger, Eric M. Leroy, Elke Mühlberger, Sergey V. Netesov (Нетёсов Сергей Викторович), Gustavo Palacios, Bernadett Pályi, Janusz T. Pawęska, Sophie J. Smither, Ayato Takada (高田礼人), Jonathan S. Towner and Victoria Wahl Image courtesy of: Jir... |
File usage
There are no pages that use this file.
