File:High grade serous carcinoma theories of origin diagram.png
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Summary
| Description |
English: Top half depicts how a stem cell in the ovarian surface epithelium may become enclosed in the ovary during ovulation and form part of a cortical inclusion cyst (CIC). This cyst may then undergo Mullerian metaplasia followed by malignant transformation into a Type I tumour (i.e. one that has a precursor). Alternatively the CIC may simply undergo malignant transformation and develop into a Type II tumour (such as HGSC) de novo.
Lower half of image describes how a fimbrial stem cell (or insome cases a serous tubal intraepithelial carcinoma) may become enclosed in the ovary during ovulation and form part of a cortical inclusion cyst that can undergo malignant transformation into a Type II tumour. |
| Date | |
| Source | Own work |
| Author | Ainenicaomh |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 18:30, 25 September 2016 | | 1,711 × 1,158 (554 KB) | commons>Cmdrjameson | Compressed with pngout. Reduced by 337kB (37% decrease). |
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