File:Anaplastic astrocytoma - very high mag - cropped.jpg

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Summary

Description
English: Very high magnification micrograph of an anaplastic astrocytoma. H&E stain.

The typical features are present:

  • Marked nuclear atypia.
  • Elongated nuclei (consistent with derivation from an astrocyte ).
  • Mitoses.
  • Fine fibrillary processes (consistent with a glial cell population).
  • Cytoplasmic staining of atypical cells with GFAP.
  • p53 immunohistochemical stain positivity.
  • High proliferative rate based on Ki-67 staining.

Related images

  • Low mag.
    Low mag.
  • Intermed. mag.
    Intermed. mag.
  • High mag.
    High mag.
  • Very high mag.
    Very high mag.
  • GFAP. Very high mag.
    GFAP. Very high mag.
  • Ki-67. High mag.
    Ki-67. High mag.
  • p53. Very high mag.
    p53. Very high mag.
Source Own work
Author Nephron

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current03:10, 21 November 2010Thumbnail for version as of 03:10, 21 November 20102,625 × 1,750 (2.3 MB)commons>Nephron{{Information |Description={{en|1=Very high magnification micrograph of an '''anaplastic astrocytoma'''. H&E stain. The typical features are present: *Marked nuclear atypia. *Elongated nuclei

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