Fibroma of tendon sheath

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Fibroma of tendon sheath
Photomicrograph of a fibroma of tendon sheath of the finger
SpecialtyPlastic surgery

Fibroma of tendon sheath is a benign tumor that presents as a small subcutaneous nodule that slowly increases in size.[1] The tumors often have a multinodular growth pattern, with individual nodules being composed of bland, slender, spindle-shaped cells (myofibroblasts) in a dense, fibrous matrix.”[2] A common microscopic finding is the presence of elongated, slit-like blood vessels.[2] The lesions nearly always arise in the distal portions of the extremities.[2] They often occur on the fingers, hands, toes, or feet. Although they are benign, they may recur in up to 40% of cases.[1]

Although they may be regarded as a tumor of the skin, the lesions arise from tendons and aponeuroses in superficial sites, and are therefore properly classified as in the category "soft tissue tumor."[2] The World Health Organization, 2020, reclassified these tumors as a specific, benign tumor type in a broad category of soft tissue neoplasms termed fibroblastic and myofibroblastic tumors.[3]

The biological nature of Fibroma of tendon sheath is not known, but the category appears to comprise a number of different pathologic processes.[2] It is considered that about one-third of the lesions in this category may be acral variants of the entity, nodular fasciitis.[2]

Multiple non-movable firm indolent deep seated nodules

See also


  1. 1.0 1.1 Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. pp. 1820, 1821. ISBN 978-1-4160-2999-1.
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Pulitzer DR, Martin PC, Reed RJ (June 1989). "Fibroma of Tendon Sheath (A Clinicopathologic Study of 32 Cases)". American Journal of Surgical Pathology. 13 (6): 472–479. doi:10.1097/00000478-198906000-00003. PMID 2729499.
  3. Sbaraglia M, Bellan E, Dei Tos AP (April 2021). "The 2020 WHO Classification of Soft Tissue Tumours: news and perspectives". Pathologica. 113 (2): 70–84. doi:10.32074/1591-951X-213. PMC 8167394. PMID 33179614.