Ferrous salt/folic acid

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Ferrous salt/folic acid
Combination of
Ferrous saltmineral
Folic acidvitamin
Trade namesFefol, Galfer FA, others
Clinical data
Defined daily dose0.4 gram (by mouth)
10 mg (parenteral)[1]
External links
AHFS/Drugs.comMultum Consumer Information

Ferrous salt/folic acid is a supplement used to prevent iron deficiency and folic acid deficiency during pregnancy.[2] It can also be used to treat iron deficiency anemia.[2] It is a fixed dose combination of ferrous salt and folic acid.[2] It is taken by mouth.[2]

Side effects may include dark stools, constipation, and abdominal pain.[2] Caution is advised in people with hemochromatosis.[3] Excessive use in children can cause serious problems.[3]

Ferrous salt/folic acid was approved for medical use in the United States as early as 1946.[4] It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system.[5] The wholesale cost in the developing world is about 0.07 to 1.02 USD a month.[6] It is not currently commercially available as a combination in the United States.[4] In the United Kingdom, it costs the NHS about £2.64 to £4.25 per month.[7]


The defined daily dose is 0.4 gram (by mouth) or 10 mg (parenteral)[1]


  1. 1.0 1.1 "WHOCC - ATC/DDD Index". www.whocc.no. Retrieved 18 September 2020.
  2. 2.0 2.1 2.2 2.3 2.4 World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. pp. 249–50. hdl:10665/44053. ISBN 9789241547659.
  3. 3.0 3.1 "Fefol Spansule Capsules - Summary of Product Characteristics (SPC) - (eMC)". www.medicines.org.uk. 2 April 2013. Archived from the original on 20 December 2016. Retrieved 18 December 2016.
  4. 4.0 4.1 "Ferrous sulfate and folic acid medical facts from Drugs.com". www.drugs.com. Archived from the original on 21 December 2016. Retrieved 18 December 2016.
  5. World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
  6. "Ferrous Salt + Folic Acid". International Drug Price Indicator Guide. Retrieved 8 December 2016.
  7. British national formulary : BNF 69 (69 ed.). British Medical Association. 2015. p. 661. ISBN 9780857111562.

External links