From WikiProjectMed
Jump to navigation Jump to search
Combination of
EthambutolAnti-tuberculosis medication
IsoniazidAnti-tuberculosis medication
Clinical data
  • US: C (Risk not ruled out)
Defined daily dosenot established[1]

Ethambutol/isoniazid is a medication used to treat tuberculosis.[2] It is a fixed dose combination of ethambutol and isoniazid.[2] It is used along with other antituberculosis medication.[2] It is taken by mouth.[2]

Side effects are those of the underlying medications.[2] More common side effects include poor coordination, numbness, and liver problems.[3] Liver problems may be severe and are more likely in people over the age of 50.[3] Use is not recommended in children.[2] It is unclear if use in pregnancy is safe for the baby.[3]

It was removed from the World Health Organization's List of Essential Medicines in 2019.[4] The wholesale cost in the developing world is about 1.47 to 1.99 USD a month.[5] The combination product is not available in Canada or in the United States.[3]


The defined daily dose is not established[1]


  1. 1.0 1.1 "WHOCC - ATC/DDD Index". Archived from the original on 2 August 2020. Retrieved 18 September 2020.
  2. 2.0 2.1 2.2 2.3 2.4 2.5 World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. p. 140. hdl:10665/44053. ISBN 9789241547659.
  3. 3.0 3.1 3.2 3.3 "Ethambutol and Isoniazid Drug Information, Professional". November 1998. Archived from the original on 21 December 2016. Retrieved 18 December 2016.
  4. World Health Organization (2019). Executive summary: the selection and use of essential medicines 2019: report of the 22nd WHO Expert Committee on the selection and use of essential medicines. Geneva: World Health Organization. hdl:10665/325773. WHO/MVP/EMP/IAU/2019.05. License: CC BY-NC-SA 3.0 IGO.
  5. "Ethambutol + Isoniazid". International Drug Price Indicator Guide. Archived from the original on 22 January 2018. Retrieved 8 December 2016.

External links