Envelysin

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Envelysin
Identifiers
EC no.3.4.24.12
CAS no.50812-13-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
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NCBIproteins

Envelysin (EC 3.4.24.12, sea-urchin-hatching proteinase, hatching enzyme, chorionase, chorion-digesting proteinase, chymostrypsin, sea urchin embryo hatching enzyme) is an enzyme.[1][2][3][4] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins of the fertilization envelope and dimethylcasein

This enzyme is a glycoprotein from various members of the class Echinoidea.

References

  1. ^ Barrett D, Edwards BF (1976). Hatching enzyme of the sea urchin Strongylocentrotus purpuratus. Methods in Enzymology. Vol. 45. pp. 354–73. doi:10.1016/s0076-6879(76)45032-2. PMID 1012003.
  2. ^ Lepage T, Gache C (March 1989). "Purification and characterization of the sea urchin embryo hatching enzyme". The Journal of Biological Chemistry. 264 (9): 4787–93. doi:10.1016/S0021-9258(18)83659-6. PMID 2925668.
  3. ^ Lepage T, Gache C (September 1990). "Early expression of a collagenase-like hatching enzyme gene in the sea urchin embryo". The EMBO Journal. 9 (9): 3003–12. doi:10.1002/j.1460-2075.1990.tb07493.x. PMC 552018. PMID 2167841.
  4. ^ Nomura K, Tanaka H, Kikkawa Y, Yamaguchi M, Suzuki N (June 1991). "The specificity of sea urchin hatching enzyme (envelysin) places it in the mammalian matrix metalloproteinase family". Biochemistry. 30 (25): 6115–23. doi:10.1021/bi00239a005. PMID 1711895.

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