|Trade names||LMD, Rheomacrodex, others|
|Other names||Low viscosity dextran|
|Main uses||Expand blood volume|
|Side effects||Volume overload, kidney problems, acidosis, allergic reactionss, poor blood clotting|
|US NLM||Dextran 40|
|Chemical and physical data|
|Molar mass||70,000 Da|
Dextran 40, sold under the brand name LMD among others, is a type of fluid given by injection into a vein to expand blood volume. Specifically it is used for shock such as that caused by bleeding or burns when blood transfusions are not quickly available. However, it does not carry oxygen.
Side effects may include volume overload, kidney problems, acidosis, allergic reactionss, and poor blood clotting. It is not recommended in severe kidney failure, heart failure, or clotting disorders. Use may interfere with certain blood tests.
Dextran 40 came into medical use in 1961. It is a glucose polymer with a typical molecular weight of 40 kDa. It works by pulling fluid from the extravascular space into the blood vessels. It is a non protein based colloid solution.
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