|Other names: CDD or Lionitis|
|Craniodiaphyseal dysplasia has an autosomal recessive pattern of inheritance|
Craniodiaphyseal dysplasia (CDD), also known as lionitis, is an extremely rare autosomal recessive bone disorder that causes calcium to build up in the skull, disfiguring the facial features and reducing life expectancy.
Signs and symptoms
The clinical presentation includes the following:
The underlying genetics are uncertain.
Among the medical signs are dacryocystitis, seizures, intellectual disability, and paralysis, each of which is a complication resulting from the diminutive foramina. A common sign reported as a result of the disease has been widely spaced eyes.
In terms of treatment, there is no cure for this condition, management depends on the symptoms displayed by the affected individual
In the American medical drama Grey's Anatomy episode "Yesterday", Jesse Plemons plays a teenage boy suffering from lionitis. The main character of the two-issue comic book miniseries Friday the 13th: How I Spent My Summer Vacation by Wildstorm Productions is a 13-year-old boy suffering from the disorder. In the anthology television series [[American Horror Story]] season 1, Beauregard, the brother of Tate and Adelaide, suffered from lionitis.
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- Craniodiaphyseal dysplasia Archived 2021-04-21 at the Wayback Machine at orpha.net Archived 2008-03-15 at the Wayback Machine