Chlorquinaldol

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Chlorquinaldol
Skeletal formula of chlorquinaldol
Names
Preferred IUPAC name
5,7-Dichloro-2-methylquinolin-8-ol
Other names
Anginazol; Lacoid, Nerisone
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.000.718 Edit this at Wikidata
KEGG
UNII
  • InChI=1S/C10H7Cl2NO/c1-5-2-3-6-7(11)4-8(12)10(14)9(6)13-5/h2-4,14H,1H3 checkY
    Key: GPTXWRGISTZRIO-UHFFFAOYSA-N checkY
  • InChI=1/C10H7Cl2NO/c1-5-2-3-6-7(11)4-8(12)10(14)9(6)13-5/h2-4,14H,1H3
    Key: GPTXWRGISTZRIO-UHFFFAOYAU
  • Clc1c(O)c2nc(ccc2c(Cl)c1)C
Properties
C10H7Cl2NO
Molar mass 228.07 g/mol
Pharmacology
D08AH02 (WHO) G01AC03 (WHO), P01AA04 (WHO), R02AA11 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Chlorquinaldol is an antimicrobial agent and antiseptic.[1] It is a chlorinated derivative of the popular chelating agent 8-hydroxyquinoline. It is applied topically as a cream and internally as a losenge.[2]

It was marketed by Geigy as an intestinal antiseptic and amebicide with the trade name Siosteran.[citation needed]

References

  1. ^ Mett H, Gyr K, Zak O, Vosbeck K (July 1984). "Duodeno-pancreatic secretions enhance bactericidal activity of antimicrobial drugs". Antimicrob. Agents Chemother. 26 (1): 35–8. doi:10.1128/aac.26.1.35. PMC 179912. PMID 6236746.
  2. ^ Kutscher, Bernhard (2020). "Dermatologicals ( D ), 4. Antiseptics and Disinfectants ( D 08), Anti‐Acne Preparations ( D 10), and Other Dermatological Preparations ( D 11)". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. pp. 1–22. doi:10.1002/14356007.w08_w03. ISBN 978-3527306732.


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