Calcineurin inhibitor
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| Calcineurin inhibitor | |
|---|---|
| Drug class | |
| Clinical data | |
| Common types | Cyclosporine, tacrolimus, pimecrolimus, voclosporin[1] |
Calcineurin inhibitors are a class of medication used to decrease immune function.[1] They are used to treat atopic dermatitis, lupus, and interstitial lung disease.[2][1] They may be used after organ transplant.[1] They may be applied as a cream, take by mouth, or injected into a vein.[2]
Common side effects of creams include skin burning.[2] Lymphoma does not appear to be a concern with the creams.[2] They work by blocking the action of calcineurin.[3] Types include cyclosporine, tacrolimus, pimecrolimus and voclosporin.[2][1]
In Canada 30 grams of tacrolimus costs about 100 CAD as of 2023.[2]
Cost
The cost in Canada of tacrolimus cream at about 100 CAD as of 2023 is more than the alternative betamethasone cream at about 13 CAD.[2]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Safarini, Omar A.; Keshavamurthy, Chandana; Patel, Preeti (2023). "Calcineurin Inhibitors". StatPearls. StatPearls Publishing. Archived from the original on 18 April 2023. Retrieved 25 July 2023.
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Ton, Joey (24 July 2023). "#345 Fancy Creams for Scaly Skin: Topical calcineurin inhibitors for atopic dermatitis (Free)". CFPCLearn. Archived from the original on 27 July 2023. Retrieved 25 July 2023.
- ↑ "List of Calcineurin inhibitors". Drugs.com. Archived from the original on 23 December 2022. Retrieved 25 July 2023.