Cadila Pharmaceuticals

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Not to be confused with Cadila Healthcare.

Cadila Pharmaceuticals Limited
Company typePrivate
IndustryPharmaceuticals
Founded1951
FounderIndravadan Modi
Headquarters
Ahmedabad, Gujarat
,
India
Key people
Rajiv Modi
(Chairman and Managing Director)
ProductsAPIs, generic drugs
Services
RevenueIncrease ₹3,675 crore (US$460 million) (FY23)[1]
Decrease ₹−10 crore (US$−1.3 million) (FY23)[1]
Number of employees
8,000
SubsidiariesIRM Ltd
Websitewww.cadilapharma.com

Cadila Pharmaceuticals is an Indian multinational pharmaceutical company based in Ahmedabad. The company's operations focus on manufacturing products ranging from active pharmaceutical intermediates, finished formulations, food supplements, biotechnology products and pharmaceutical machinery.[2]

History

Indravadan Modi, Founder

Cadila Laboratories

In 1951 Indravadan A Modi had quit his job as a chemist in a Mumbai firm to start Cadila Laboratories with childhood friend Ramanbhai Patel. The company started in a rented bungalow with a capital of Rs 25,000 and achieved a turnover of around Rs 1.25 lakh in its first year of operation.[3]

1995: Birth of Cadila Pharmaceuticals

The Modi and Patel families decided to split the business in 1995, two entities were formed - Cadila Pharmaceuticals Ltd (owned and controlled by Indravadan Modi and his son Rajiv Modi) and Cadila Healthcare (owned by Ramanbhai Patel and his son Pankaj Patel family).[3]

Operations

Cadila Pharmaceuticals has its formulation manufacturing facilities at Dholka, Gujarat (India); Samba, Jammu (India) and at Addis Ababa (Ethiopia) and 2 API manufacturing facilities are located at Ankleshwar, Gujarat. The manufacturing facility at Dholka and the API unit at Ankleshwar in Gujarat are USFDA-certified; the overseas manufacturing facility at Ethiopia is the WHO - cGMP compliant facility.[4]

Research

Cadila Pharmaceuticals has established a dedicated R&D facility, spread over 1,05,000 sq. ft. area at Dholka, Gujarat, India which is staffed by 300 scientists.[citation needed]

The company has five IND dossiers filed with the USFDA for pulmonary tuberculosis, lung cancer, prostate cancer, bladder cancer and melanoma. The company has submitted ten ANDAs.[5]

Products and services

The Samba plant specializes in the production of a wide variety of drugs, totaling 140 types. It was commissioned in September 2002, showcasing Cadila Pharmaceuticals' commitment to expanding its manufacturing capabilities. With an expansive area of 11 acres, the plant represents a significant investment in pharmaceutical manufacturing infrastructure in the region. The project type being derivative indicates a focus on producing pharmaceutical derivatives or derivative-based products. The total budget for the project is 100 crores.The project was expected to be complete within around 800 days from the date of commencement. Cadila Pharmaceuticals is the only Indian manufacturer of natural Streptokinase and Hyaluronic Acid products. The company was also the first in the world to introduce Rabeprazole in IV form – 'Rabeloc'.[6] In 2009, the world's first boosted-Rifampicin fixed-dose combination for the treatment of Tuberculosis – 'Risorine'[7] and world's first drug combination for prevention of Cardiovascular Diseases – 'Polycap' were introduced by Cadila Pharmaceuticals.[8] For the patients with Non Small Cell Lung Cancer (NSCLC), the company introduced 'Mycidac-C' - first in the class active immunotherapy as well as drug targeting Desmocollin.[9] Some of the top brands of the company are Aciloc, Envas, Calcirol, Haem Up, Vasograin, Tricort, Fludac, Rabiloc, Trigan-D, Mycobutol and Sepsivac.[citation needed]

On March 4, 2024, Cadila Pharmaceuticals announced the launch of Cadiflu Tetra, a quadrivalent influenza vaccine approved for use in adults and children by the Drugs Controller General of India (DCGI), using proprietary technology with nano-sized particles to mimic the virus's external structure without containing its genetic material.[10]

Alliances

In 2019, Cadila Pharmaceuticals formed a partnership with Norwegian start-up, Serca Pharmaceuticals to develop new treatment for heart patients.[11]

Controversies

Company

In 2014, a cautionary notice appeared on the FDA website highlighting substantial manufacturing practice discrepancies discovered by inspectors in March at Cadila Pharmaceuticals' Ankleshwar facility in Gujarat.[12] This incident marked one among several Indian pharmaceutical companies receiving regulatory warnings from the FDA, indicating increased scrutiny on generic drugmakers.[13] A similar kind of notices were again issued in 2016[14] and 2019.[15]

Management

In 2018, the chairman of the company, Rajiv Modi, went through a widely publicized and contentious divorce with his wife, Monica, who comes from a prominent Mumbai-based business family of Garware. At that time, Modi transferred ₹200 crore (US$25 million) to Monica, who relinquished her rights, while custody of their son was awarded to Modi.[16][17]

In December 2023, Gujarat Police complied with a Gujarat High Court order, initiating a case against Rajiv Modi.[18] The case involves accusations of rape, assault, and intentional insult by a Bulgarian woman employed as a flight attendant and personal assistant at the company. She reported multiple instances of sexual harassment from February to March 2023, stating that she was terminated in April 2023 after resisting Modi's alleged “illicit demands”.[19][20]

References

  1. ^ a b "Cadila Pharmaceuticals Limited". Crediwatch. Retrieved 18 December 2023.
  2. ^ Bureau, BL Ahmedabad (22 March 2023). "Cadila Pharma to expand and upgrade its existing facilities in Gujarat". BusinessLine. Retrieved 11 September 2023.
  3. ^ a b Das, Sohini (28 January 2014). "Carrying the legacy forward: Rajiv Modi" – via Business Standard.
  4. ^ Financial Express 28 January 2013
  5. ^ "Welcome to India in Business". www.indiainbusiness.nic.in. Archived from the original on 7 July 2014. Retrieved 24 March 2014.
  6. ^ Bureau, Our Regional (16 July 2004). "Cadila Pharma unveils acidity drug in IV form" – via Business Standard.
  7. ^ "Cadila launches new drug for TB treatment". dna. 31 October 2009.
  8. ^ "Cadila Pharmaceuticals launches Polycap, which reduces cardiovascular and stroke risk substantially". The Financial Express. 2 April 2009.
  9. ^ "Economic Times 21 November 2013".
  10. ^ Bureau, BL Ahmedabad (4 March 2024). "Cadila Pharmaceuticals launches advanced Quadrivalent Influenza Vaccine". BusinessLine. Retrieved 4 March 2024.
  11. ^ "Cadila Pharma inks pact with Norwegian start-up to develop new treatment for heart patients". @businessline. Retrieved 11 January 2019.
  12. ^ Mishra, Digbijay; Das, Sohini (13 November 2014). "US FDA scolds Cadila Pharma over manufacturing practice in Gujrat plant". Retrieved 6 January 2024.
  13. ^ "FDA warns Cadila Pharma over drug production processes". Reuters. 12 November 2014. Retrieved 6 January 2023.
  14. ^ RAJAGOPAL, DIVYA (1 January 2016). "Cadila gets US FDA warning for violating standards at Moraiya and Ahmedabad plants". The Economic Times. ISSN 0013-0389. Retrieved 6 January 2024.
  15. ^ Research, Center for Drug Evaluation and (28 November 2022). "Cadila Healthcare Limited - 584856 - 10/29/2019". Center for Drug Evaluation and Research. Retrieved 6 January 2024.
  16. ^ "Gujarat: Cadila Pharma owner pays wife Rs 200 crore". The Times of India. 31 October 2018. ISSN 0971-8257. Retrieved 6 January 2024.
  17. ^ "Cadila Pharmaceuticals boss Rajiv Modi swallows a Rs 200-cr divorce pill". DNA India. Retrieved 6 January 2024.
  18. ^ Khatri, Dhananjay (24 December 2023). "Gujarat HC orders probe against Cadila Pharma CMD into rape allegations". CNBCTV18. Retrieved 6 January 2024.
  19. ^ "Cops register FIR against Cadila CMD for rape of Bulgarian woman after Gujarat HC order". The Indian Express. 31 December 2023. Retrieved 6 January 2024.
  20. ^ PTI. "Gujarat police register rape case against Cadila Pharma CMD after HC order". Deccan Herald. Retrieved 6 January 2024.

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