CYP18 family

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Cytochrome P450, family 18, also known as CYP18, is an animal cytochrome P450 family found in insect genomes.[1] It is involved in insecticide resistance.[2] The first member gene identified was CYP18A1, from a Drosophila melanogaster fly, acting as a dimethylnitrosamine demethylase.[3]

References

  1. ^ Nelson, DR (November 1998). "Metazoan cytochrome P450 evolution". Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology. 121 (1–3): 15–22. doi:10.1016/s0742-8413(98)10027-0. PMID 9972448.
  2. ^ Jin, Y; Gao, Y; Zhang, H; Wang, L; Yang, K; Dong, H (January 2020). "Detoxification enzymes associated with butene-fipronil resistance in Epacromius coerulipes". Pest Management Science. 76 (1): 227–235. doi:10.1002/ps.5500. PMID 31150148. S2CID 171093218.
  3. ^ Bassett, MH; McCarthy, JL; Waterman, MR; Sliter, TJ (4 July 1997). "Sequence and developmental expression of Cyp18, a member of a new cytochrome P450 family from Drosophila". Molecular and Cellular Endocrinology. 131 (1): 39–49. doi:10.1016/s0303-7207(97)00093-2. PMID 9256362. S2CID 38929634.


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