Bowenoid papulosis

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Bowenoid papulosis
Bowenoid papulosis
SpecialtyDermatology, gynecology

Bowenoid papulosis is a skin condition characterized by small dark bumps in the genital area of both males and females.[1] There may be one or many, and can generally be found on the penis or near the vulva, but may present on the face or neck, particularly of men.[1] They are associated with human papillomavirus, the causative agent of genital warts.[2]

It is considered as a pre-malignant condition. Other terms used to describe the condition are: Erythroplasia of Queyrat, Squamous cell carcinoma in situ and Bowen's disease. The term bowenoid papulosis was coined in 1977 by Kopf and Bart and is named after dermatologist John Templeton Bowen.[3][4][5] The term “intraepithelial neoplasia” defines a premalignant intraepithelial change.

On the vulva it is termed VIN (vulvar or vulval intraepithelial neoplasia); on the penis, PIN (penile intraepithelial neoplasia); and on or around the anus, AIN (anal intraepithelial neoplasia). The terminology has been very confusing and it is now recommended that the terms Bowen's disease, erythroplasia of Queyrat, and bowenoid papulosis should not be used for lesions in the anogenital area. However, dermatologists still recognize a distinct clinical variant, bowenoid papulosis, characterized by discrete papules in a younger age group and a tendency for spontaneous regression. Additionally, some authorities believe that erythroplasia of Queyrat and Bowen's disease remain useful terms in men.

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  1. 1.0 1.1 James, William D.; Elston, Dirk; Treat, James R.; Rosenbach, Misha A.; Neuhaus, Isaac (2020). "19. Viral diseases". Andrews' Diseases of the Skin: Clinical Dermatology (13th ed.). Edinburgh: Elsevier. p. 408. ISBN 978-0-323-54753-6. Archived from the original on 2022-09-20. Retrieved 2022-09-04.
  2. Chamli, Amal; Zaouak, Anissa (2022). "Bowenoid Papulosis". StatPearls. StatPearls Publishing. Archived from the original on 2021-07-26. Retrieved 2022-09-04.
  3. synd/3996 at Who Named It?
  4. Kopf AW, Bart RS (1977). "Tumor conference No. 11: multiple bowenoid papules of the penis: a new entity?". J Dermatol Surg Oncol. 3 (3): 265–9. doi:10.1111/j.1524-4725.1977.tb00289.x. PMID 874134.
  5. Wade TR, Kopf AW, Ackerman AB (October 1978). "Bowenoid papulosis of the penis". Cancer. 42 (4): 1890–903. doi:10.1002/1097-0142(197810)42:4<1890::AID-CNCR2820420430>3.0.CO;2-C. PMID 361215.

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