Atrolysin F

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Atrolysin F
Identifiers
EC no.3.4.24.45
CAS no.172306-52-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins

Atrolysin F (EC 3.4.24.45, Crotalus atrox metalloendopeptidase, hemorrhagic toxin f, Crotalus atrox metalloendopeptidase f) is an enzyme.[1] This enzyme catalyses the following chemical reaction

Cleavage of Val2-Asn, Gln4-His, Leu6-Cys, His10-Leu, Ala14-Leu and Tyr16-Leu bonds in insulin B chain

This endopeptidase is present in the venom of the western diamondback rattlesnake (Crotalus atrox).

References

  1. ^ Nikai T, Mori N, Kishida M, Sugihara H, Tu AT (June 1984). "Isolation and biochemical characterization of hemorrhagic toxin f from the venom of Crotalus atrox (western diamondback rattlesnake)". Archives of Biochemistry and Biophysics. 231 (2): 309–19. doi:10.1016/0003-9861(84)90393-x. PMID 6375570.

External links