|Trade names||Tenoretic, Tenoret, others|
|Defined daily dose||not established|
|AHFS/Drugs.com||FDA Professional Drug Information|
Atenolol/chlorthalidone, also known as co-tenidone, is a combination medication used to treat high blood pressure. It is made up of atenolol, a beta-blocker and chlortalidone, a diuretic. It is not recommended as an initial treatment but may be used in those who are taking atenolol and chlortalidone individually. It is taken by mouth.
Common side effects include gastrointestinal upset and gout. Serious side effects may include liver problems, pancreatitis, and psychosis. Use is not recommended during pregnancy. Use during breastfeeding may harm the baby. Atenolol works by blocking β1-adrenergic receptors in the heart, thus decreasing the heart rate and workload. Chlorthalidone works by increasing the amount of sodium lost by the kidneys.
The combination was approved for medical use in the United States in 1984. It is available as a generic medication. A month supply in the United Kingdom costs the NHS less than 2 £ as of 2019. In the United States the wholesale cost of this amount is about US$12.30. In 2017, it was the 295th most commonly prescribed medication in the United States, with more than one million prescriptions.
- "WHOCC - ATC/DDD Index". www.whocc.no. Retrieved 9 September 2020.
- "Tenoret 50 mg/12.5 mg film coated tablets - Summary of Product Characteristics (SmPC)". (emc). 29 November 2019. Retrieved 4 May 2020.
- "DailyMed - atenolol and chlorthalidone tablet". dailymed.nlm.nih.gov. Retrieved 18 April 2019.
- British national formulary : BNF 76 (76 ed.). Pharmaceutical Press. 2018. p. 153. ISBN 9780857113382.
- "Atenolol and Chlorthalidone Tablets - FDA prescribing information, side effects and uses". Drugs.com. Retrieved 18 April 2019.
- "Atenolol Monograph for Professionals". Drugs.com. American Society of Health-System Pharmacists. Retrieved 18 April 2019.
- "NADAC as of 2019-02-27". Centers for Medicare and Medicaid Services. Retrieved 3 March 2019.
- "The Top 300 of 2020". ClinCalc. Retrieved 11 April 2020.
- "Atenolol; Chlorthalidone - Drug Usage Statistics". ClinCalc. Retrieved 11 April 2020.
- "Atenolol mixture with chlorthalidone". Drug Information Portal. U.S. National Library of Medicine.
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